Evidence map›Paper›PMID 35155858›Full record

ArticleKidney international reports2022

Implantable Loop Recorder Monitoring and the Incidence of Previously Unrecognized Atrial Fibrillation in Patients on Hemodialysis.

Bruce A Koplan, Wolfgang C Winkelmayer, Alexandru I Costea, Prabir Roy-Chaudhury, James A Tumlin, Vijay Kher, Don E Williamson, Saurabh Pokhariyal, David M Charytan, Monitoring in Dialysis (MiD) Investigators and Committees

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 2 countries.

Bruce A KoplanCardiology Division, Brigham & Women's Hospital, Boston, Massachusetts, USA.
Wolfgang C WinkelmayerSection of Nephrology, Baylor College of Medicine, Houston, Texas, USA.
Alexandru I CosteaCardiology Division, University of Cincinnati School of Medicine, Cincinnati, Ohio, USA.
Prabir Roy-ChaudhuryDepartment of Medicine, University of North Carolina Kidney Center, Chapel Hill, North Carolina, USA.
James A TumlinGeorgia Nephrology Clinical Research Institute, Atlanta, Georgia, USA.
Vijay KherMedanta Kidney & Urology Institute, Medanta, The Medicity, Gurugram, India.
Don E WilliamsonSoutheastern Clinical Research Institute, Augusta, Georgia, USA.
Saurabh PokhariyalDivision of Nephrology and Renal Transplantation, Manipal Hospitals, Dwarka, New Delhi, India.
David M CharytanNephrology Division, NYU Grossman School of Medicine, New York, New York, USA.
Monitoring in Dialysis (MiD) Investigators and Committees
Clinical Research Institute · USNew York University · USBaylor College of Medicine · USBrigham and Women's Hospital · USGeorgia Clinical Research · USManipal Hospital · INMedanta The Medicity · INUniversity of Cincinnati · USUniversity of North Carolina at Chapel Hill · US

Funding

The Atrial Fibrillation - Factor Identification to Risk Modification Study in HDR01DK095024 · NIDDK · STANFORD UNIVERSITY · PI WINKELMAYER, WOLFGANG CHRISTOPH · 2012 to 2023
$4.3M
Modulation of VSMC phenotype through the Insulin Receptor Substrate-1/Kruppel-like factor-4 signal transduction pathway: a Novel Target for AVF DysfunctionR01DK132328 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PRABIR ROY-CHAUDHURY, Gang Xi · 2022 to 2026
$2.7M
NIDDK NIH HHS R01 DK095024NIDDK NIH HHS R01 DK132328
6 · The paper itself

Abstract

introductionAtrial fibrillation (AF) is common in patients with kidney failure on hemodialysis (KF-HD). We determined both AF incidence and burden in patients with KF-HD using implantable loop recorder (ILR) monitoring

methodsPatients with KF-HD were enrolled and received an ILR. In 6 monitoring months, the incidence of AF events lasting ≥6 minutes was captured. Demographic, clinical, and dialysis characteristics were collected, and associations with incident AF were estimated using negative binomial regression models and expressed as incidence rate ratios and 95% CIs.

resultsWe enrolled 66 patients with KF-HD (mean age = 56 years, 70% male); 59 (90%) were without previously diagnosed AF. AF lasting ≥6 minutes was detected in 18 of 59 subjects (31%) without previously diagnosed AF and in 5 of 7 subjects (71%) with a previous AF diagnosis. Among the 23 with detected AF, episodes were present on 16% of patient days. Although 14 of 23 patients (61%) had AF on <5% of monitored days, the average duration of AF episodes was <1 hour in 13 of 23 patients (52%). Among patients with AF ≥6 minutes, 19 of 23 (83%) had a CHA

conclusionNew AF was detected in approximately one-third of patients with KF-HD. AF affects a substantial proportion of patient days and may be an underappreciated cause of stroke in KF-HD.

Indexed as

arrhythmiasatrial fibrillationend stage kidney diseae (ESKD)hemodialysisimplantable loop recorderkidney failure

Identifiers

PMID35155858
PMCPMC8821036
OpenAlexW3206303710

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.