Evidence map›Paper›PMID 35155816›Full record

ArticleAutism & developmental language impairments

Motor speech impairment predicts expressive language in minimally verbal, but not low verbal, individuals with autism spectrum disorder.

Karen Chenausky, Amanda Brignell, Angela Morgan, Helen Tager-Flusberg

Open access · goldAbstract read
In one paragraph

Article in Autism & developmental language impairments. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Atypical structural connectivity of language networks in autism spectrum disorder: A meta-analysis of diffusion tensor imaging studies.Autism research : official journal of the International Society for Autism Research · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. An Acoustic Analysis of Speech Motor Performance in Autistic Children.Journal of speech, language, and hearing research : JSLHR · 2025
    Article
  11. Article
  12. Article
  13. Profiles of minimally verbal autistic children: Illuminating the neglected end of the spectrum.Autism research : official journal of the International Society for Autism Research · 2024
    Article
  14. Article
  15. Article
  16. Vowel distinctiveness as a concurrent predictor of expressive language function in autistic children.Autism research : official journal of the International Society for Autism Research · 2024
    Article
  17. Receptive language and receptive-expressive discrepancy in minimally verbal autistic children and adolescents.Autism research : official journal of the International Society for Autism Research · 2024
    Article
  18. Speech Development Across Subgroups of Autistic Children: A Longitudinal Study.Journal of autism and developmental disorders · 2023
    Article
  19. Oromotor skills in autism spectrum disorder: A scoping review.Autism research : official journal of the International Society for Autism Research · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Karen ChenauskySargent College, Boston University, Boston, MA, USA.ORCID 0000-0002-4294-9228
Amanda BrignellSpeech and Language, Murdoch Children's Research Institute, Melbourne, Australia; University of Melbourne, Melbourne, Australia.
Angela MorganSpeech and Language, Murdoch Children's Research Institute, Melbourne, Australia; University of Melbourne, Melbourne, Australia.
Helen Tager-FlusbergSargent College, Boston University, Boston, MA, USA.
Boston University · USThe University of Melbourne · AU

Funding

Testing the efficacy of a novel intervention for minimally verbal children with P50DC013027 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI JOSEPH, ROBERT M · 2012 to 2016
$9.4M
Advanced Research Training in Communication Sciences and DisordersT32DC013017 · NIDCD · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI Cara E. Stepp · 2016 to 2026
$4.9M
Behavioral and Neural Correlates of Melodic Intonation TherapyR01DC008796 · NIDCD · BETH ISRAEL DEACONESS MEDICAL CENTER · PI SCHLAUG, GOTTFRIED · 2008 to 2012
$2.0M
Identifying and Treating Childhood Apraxia of Speech in Minimally Verbal Children with AutismK99DC017490 · NIDCD · MGH INSTITUTE OF HEALTH PROFESSIONS · PI CHENAUSKY, KAREN V · 2019 to 2021
$298k
NIDCD NIH HHS K99 DC017490NIDCD NIH HHS P50 DC013027NIDCD NIH HHS R01 DC008796NIDCD NIH HHS T32 DC013017
6 · The paper itself

Abstract

BACKGROUND AND

aimsDevelopmental motor speech impairment has been suspected, but rarely systematically examined, in low- and minimally verbal individuals with autism spectrum disorder. We aimed to investigate the extent of motor speech impairment in this population and its relation to number of different words produced during a semi-structured language sample.

methodsVideos of 54 low-verbal and minimally verbal individuals (ages 4;4-18;10) performing portions of a speech praxis test were coded for signs of motor speech impairment (e.g., childhood apraxia of speech). Age, autism spectrum disorder severity, nonspeech oral-motor ability, speech production ability, nonverbal IQ, and receptive vocabulary were compared between groups.

resultsFour groups emerged: (1) speech within normal limits ( CONCLUSIONS AND IMPLICATIONS: If replicated, our findings have important implications for developing much-needed spoken language interventions in minimally verbal individuals with autism spectrum disorder.

Indexed as

Autism spectrum disorderchildhood apraxia of speechexpressive languagemotor speech disorderspeech

Identifiers

PMID35155816
PMCPMC8837193
OpenAlexW2951085730

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.