Evidence map›Paper›PMID 35155788›Full record

ArticleLaryngoscope investigative otolaryngology2022

Dysphagia, hypothyroidism, and osteoradionecrosis after radiation therapy for head and neck cancer.

Pihla Ranta, Eero Kytö, Linda Nissi, Ilpo Kinnunen, Tero Vahlberg, Heikki Minn, Eeva Haapio, Lassi Nelimarkka, Heikki Irjala

Open access · goldAbstract read
In one paragraph

Article in Laryngoscope investigative otolaryngology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Head and neck squamous cell carcinoma: current and emerging therapeutic strategies.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  2. Article
  3. Dysphagia at 1 Year is Associated With Mean Dose to the Inferior Section of the Brain Stem.International journal of radiation oncology, biology, physics · 2023
    Article
  4. Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Pihla RantaDepartment of Otorhinolaryngology - Head and Neck Surgery Turku University and Turku University Hospital Turku Finland.ORCID https://orcid.org/0000-0003-3211-2018
Eero KytöDepartment of Otorhinolaryngology - Head and Neck Surgery Turku University and Turku University Hospital Turku Finland.ORCID https://orcid.org/0000-0002-2567-5931
Linda NissiDepartment of Oncology and Radiotherapy Turku University and Turku University Hospital Turku Finland.
Ilpo KinnunenDepartment of Otorhinolaryngology - Head and Neck Surgery Turku University and Turku University Hospital Turku Finland.
Tero VahlbergDepartment of Clinical Medicine, Biostatistics Turku University and Turku University Hospital Turku Finland.
Heikki MinnDepartment of Oncology and Radiotherapy Turku University and Turku University Hospital Turku Finland.ORCID https://orcid.org/0000-0002-5878-4333
Eeva HaapioDepartment of Otorhinolaryngology - Head and Neck Surgery Turku University and Turku University Hospital Turku Finland.
Lassi NelimarkkaDepartment of Endocrinology, Division of Medicine Turku University and Turku University Hospital Turku Finland.
Heikki IrjalaDepartment of Otorhinolaryngology - Head and Neck Surgery Turku University and Turku University Hospital Turku Finland.ORCID https://orcid.org/0000-0003-3054-4677
Turku University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo analyze the long-term side effects of radiation therapy (RT) for head and neck cancer (HNC).

methodsRetrospective chart analysis of all 688 HNC patients treated during 2010-2015 at Turku University Hospital, Finland. All patients who survived for more than a year after RT/chemoRT were included (

resultsOne hundred and six patients (45%) reported persisting dysphagia, for which neck RT increased risk. Definitive neck RT to high-risk volume did not increase late toxicity risks compared to elective neck RT. Radiation-induced hypothyroidism (29%,

conclusionsLate toxicities of RT for HNC are common. Age, gender, tumor subsite, and neck RT affect susceptibility to long-term side effects. LEVEL OF EVIDENCE: 4.

Indexed as

dysphagia/swallowingneoplasia/malignancyradiation therapy

Identifiers

PMID35155788
PMCPMC8823172
OpenAlexW4200516163

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.