Evidence map›Paper›PMID 35155686›Full record

ArticleJournal of immunology research2022

Differential Circulating Fungal Microbiome in Prostate Cancer Patients Compared to Healthy Control Individuals.

Xu Wang, Zejun Zhou, David Turner, Michael Lilly, Tongwen Ou, Wei Jiang

Open access · goldAbstract read
In one paragraph

Article in Journal of immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Mycobiome: an underexplored kingdom in cancer.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Non-self glycan structures as possible modulators of cancer progression: would polysaccharides from Cryptococcus spp. impact this phenomenon?Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Xu WangDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, 29425 SC, USA.
Zejun ZhouState Key Laboratory of Developmental Biology of Freshwater Fish, College of Life Sciences, Hunan Normal University, Changsha 410081, China.ORCID https://orcid.org/0000-0002-2901-5041
David TurnerDepartment of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, USA.
Michael LillyDivision of Hematology and Oncology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Tongwen OuDepartment of Urology, Capital Medical University Affiliated XuanWu Hospital, 45 Changchun Street, Xicheng District, Beijing 100053, China.ORCID https://orcid.org/0000-0003-2598-7617
Wei JiangDepartment of Microbiology and Immunology, Medical University of South Carolina, Charleston, 29425 SC, USA.ORCID https://orcid.org/0000-0002-1374-053X
Medical University of South Carolina · USCapital Medical University · CNHunan Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundsInfection and inflammation play an important role in prostate cancer (PCa) etiology and pathogenesis. However, the environmental drivers for PCa are not fully understood.

methodsIn a cross-sectional study, we analyzed circulating fungal microbiome in plasma samples from age and race-matched healthy control men (

resultsThe fungal community in the plasma exhibited differences between individuals with PCa and healthy controls according to the beta diversity; there was no difference in the alpha diversity. Moreover, the relative abundance of several fungi differed between the two study groups from the class to species levels. The most significant differences were

conclusionThis is the first study to show plasma distinct fungal microbiome and its associations with PSA levels, relapse, and pathology stages in PCa patients.

Indexed as

AgedBipolarisCross-Sectional StudiesCryptococcusHealthy VolunteersHumansMaleMicrobiotaMiddle AgedNeoplasm Recurrence, LocalNeoplasm StagingPhomaProstate-Specific AntigenProstatic NeoplasmsProstate-Specific Antigen

Identifiers

PMID35155686
PMCPMC8831061
OpenAlexW4210795807

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.