Evidence map›Paper›PMID 35155685›Full record

ArticleJournal of immunology research2022

A Novel

Lanlin Zhang, Jiangyuan Du, Qian Song, Chufan Zhang, Xianghua Wu

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Journal of immunology research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. RETRACTION: A NovelJournal of immunology research · 2025
    Article
  4. High Efficacy of Rose Bengal in Reducing the Pathogenicity ofInternational journal of microbiology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Biomimetic nanoparticles for tumor immunotherapy.Frontiers in bioengineering and biotechnology · 2022
    Review
  12. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Lanlin ZhangDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Jiangyuan DuShanghai TCM-Integrated Institute of Vascular Anomalies, Shanghai TCM-Integrated Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200082, China.
Qian SongDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Chufan ZhangDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.
Xianghua WuDepartment of Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai 200032, China.ORCID https://orcid.org/0000-0001-6914-1598
Shanghai Medical College of Fudan University · CNShanghai University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dendritic cell- (DC-) based vaccination has emerged as a promising antitumour immunotherapy. However, overcoming immune tolerance and immunosuppression in the tumour microenvironment (TME) is still a great challenge. Recent studies have shown that Rose Bengal (RB) can effectively induce immunogenic cell death (ICD) in cancer cells, presenting whole tumour antigens for DC processing and presentation. However, the synergistic antitumour effect of combining intralesional RB with immature DCs (RB-iDCs) remains unclear. In the present study, we investigated whether RB-iDCs have superior antitumour effects compared with either single agent and evaluated the immunological mechanism of RB-iDCs in a murine lung cancer model. The results showed that intralesional RB-iDCs suppressed subcutaneous tumour growth and lung metastasis, which resulted in 100% mouse survival and significantly increased TNF-

Indexed as

Adaptive ImmunityAnimalsAntigen PresentationAntigens, NeoplasmCancer VaccinesCD8-Positive T-LymphocytesCell DifferentiationDendritic CellsHumansImmunizationImmunotherapyLung NeoplasmsLymphocytes, Tumor-InfiltratingMelanomaMelanoma, ExperimentalMiceAntigens, NeoplasmCancer VaccinesRose Bengal

Identifiers

PMID35155685
PMCPMC8824725
OpenAlexW4210618022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.