Evidence map›Paper›PMID 35155670›Full record

ReviewBioMed research international2022

Therapeutic Applications of Curcumin in Diabetes: A Review and Perspective.

Cristina Quispe, Jesús Herrera-Bravo, Zeeshan Javed, Khushbukhat Khan, Shahid Raza, Zehra Gulsunoglu-Konuskan, Sevgi Durna Daştan, Oksana Sytar, Miquel Martorell, Javad Sharifi-Rad and 1 more

Open access · hybridAbstract readReview
In one paragraph

Review in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
6.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 84 citations in OpenAlex.

  1. Chemical constituents in the rhizome of Curcuma longa and the pharmacological importance of curcumin hybrids.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
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  8. [Curcumin inhibits lipid metabolism in non-small cell lung cancer by downregulating the HIF-1α pathway].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 10 institutions in 7 countries.

Cristina QuispeFacultad de Ciencias de la Salud, Universidad Arturo Prat, Avda Arturo Prat 2120, Iquique 1110939, Chile.
Jesús Herrera-BravoDepartamento de Ciencias Básicas, Facultad de Ciencias, Universidad Santo Tomas, Chile.ORCID https://orcid.org/0000-0003-0739-7920
Zeeshan JavedOffice for Research Innovation and Commercialization, Lahore Garrison University, Lahore, Pakistan.
Khushbukhat KhanAtta-ur-Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad, Punjab, Pakistan.ORCID https://orcid.org/0000-0002-9946-9057
Shahid RazaOffice for Research Innovation and Commercialization, Lahore Garrison University, Lahore, Pakistan.
Zehra Gulsunoglu-KonuskanFaculty of Health Science, Nutrition and Dietetics Department, Istanbul Aydin University, Istanbul 34295, Turkey.ORCID https://orcid.org/0000-0001-6497-1912
Sevgi Durna DaştanDepartment of Biology, Faculty of Science, Sivas Cumhuriyet University, 58140 Sivas, Turkey.
Oksana SytarDepartment of Plant Physiology, Slovak University of Agriculture, A. Hlinku 2, 94976 Nitra, Slovakia.
Miquel MartorellDepartment of Nutrition and Dietetics, Faculty of Pharmacy, and Centre for Healthy Living, University of Concepción, 4070386 Concepción, Chile.ORCID https://orcid.org/0000-0003-3183-7623
Javad Sharifi-RadFacultad de Medicina, Universidad del Azuay, Cuenca, Ecuador.ORCID https://orcid.org/0000-0002-7301-8151
Daniela CalinaDepartment of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID https://orcid.org/0000-0002-1523-9116
Lahore Garrison University · PKArturo Prat University · CLIstanbul Aydın University · TRNational University of Sciences and Technology · PKSivas Cumhuriyet Üniversitesi · TRSlovak University of Agriculture in Nitra · SKUniversidad de La Frontera · CLUniversidad del Azuay · ECUniversity of Concepción · CLUniversity of Medicine and Pharmacy of Craiova · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetes is a metabolic disease with multifactorial causes which requires lifelong drug therapy as well as lifestyle changes. There is now growing scientific evidence to support the effectiveness of the use of herbal supplements in the prevention and control of diabetes. Curcumin is one of the most studied bioactive components of traditional medicine, but its physicochemical characteristics are represented by low solubility, poor absorption, and low efficacy. Nanotechnology-based pharmaceutical formulations can help overcome the problems of reduced bioavailability of curcumin and increase its antidiabetic effects. The objectives of this review were to review the effects of nanocurcumin on DM and to search for databases such as PubMed/MEDLINE and ScienceDirect. The results showed that the antidiabetic activity of nanocurcumin is due to complex pharmacological mechanisms by reducing the characteristic hyperglycemia of DM. In light of these results, nanocurcumin may be considered as potential agent in the pharmacotherapeutic management of patients with diabetes.

Indexed as

NanotechnologyBiological AvailabilityCurcuminDiabetes MellitusHumansCurcumin

Identifiers

PMID35155670
PMCPMC8828342
OpenAlexW4210785929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.