ArticleFrontiers in veterinary science2021
Inflammatory Disease Affecting the Central Nervous System in Dogs: A Retrospective Study in England (2010-2019).
Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- NMR metabolomic profiling of cerebrospinal fluid from dogs with meningoencephalitis of unknown origin demonstrates metabolic similarities to multiple sclerosis.Metabolomics : Official journal of the Metabolomic Society · 2026Article
- Increased detectability of Apolipoprotein E (ApoE) in cerebrospinal fluid samples of dogs with peracute and acute central nervous system lesions.Frontiers in veterinary science · 2026Article
- Antioxidant Strategies for Age-Related Oxidative Damage in Dogs.Veterinary sciences · 2025Review
- Retrospective Analysis of Central Nervous System Diseases in Dogs, with Special Focus on Non-Suppurative Encephalomyelitis (1962-2022).Veterinary sciences · 2025Article
- Evaluation of Cervical Myoclonus in Dogs with Spinal Diseases: 113 Cases (2014-2023).Animals : an open access journal from MDPI · 2025Article
- Clinical Features, MRI Findings, Treatment, and Outcomes in Dogs with Haemorrhagic Myelopathy Secondary to Steroid-Responsive Meningitis-Arteritis: Nine Cases (2017-2024).Veterinary sciences · 2025Article
- Usefulness of neurological assessment scales in prognosis of meningoencephalitis of unknown origin in Yorkshire Terriers.BMC veterinary research · 2025Article
- Plant Material in the Thalamus and Mesencephalon of a Young Dog.Veterinary sciences · 2025Article
- Magnetic resonance imaging findings in dogs with steroid-responsive meningitis-arteritis in the UK and their clinical significance: 53 cases (2013-2021).The Journal of small animal practice · 2025Article
- A multiplex targeted NGS panel for identifying pathogens in canine neurological and reproductive diseases.Frontiers in cellular and infection microbiology · 2025Article
- The role of regulatory T cells in central nervous system diseases in dogs: fighting with a double-edged sword toward translational discoveries.American journal of translational research · 2025Review
- Meningoencephalitis of unknown origin in dogs under veterinary referral care in England (2017-2021): a multicenter case control study.Frontiers in veterinary science · 2025Article
- Causal Agent Investigation and Treatment of Dogs Diagnosed with Discospondylitis in aVeterinary sciences · 2024Article
- Of potential new treatment targets and polythetic approach in meningoencephalitis of unknown origin: a review.Frontiers in veterinary science · 2024Review
- Predictive Value of Acute Phase Proteins for the Short-Term Outcome of Meningoencephalitis of Unknown Origin in Dogs.Animals : an open access journal from MDPI · 2023Article
- Comparison of Imaging Methods and Population Pattern in Dogs with Spinal Diseases in Three Periods between 2005 and 2022: A Retrospective Study.Veterinary sciences · 2023Article
- A comparison between neurological clinical signs, cerebrospinal fluid analysis, cross-sectional CNS imaging, and infectious disease testing in 168 dogs with infectious or immune-mediated meningoencephalomyelitis from Brazil.Frontiers in veterinary science · 2023Article
- Clinical presentation, treatment, and outcome of 24 dogs with bacterial meningitis or meningoencephalitis without empyema (2010-2020).Journal of veterinary internal medicine · 2023Article
- Perspectives on pharmacologic strategies in the management of meningoencephalomyelitis of unknown origin in dogs.Frontiers in veterinary science · 2023Review
- Risk Factors Regarding Dog Euthanasia and Causes of Death at a Veterinary Teaching Hospital in Italy: Preliminary Results.Veterinary sciences · 2022Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The epidemiology of inflammatory diseases affecting the central nervous system (CNS) in dogs is largely unknown. We aimed to report the relative proportion of different causes of inflammatory disease affecting the CNS in dogs and identify predictors for infectious vs. immune-mediated conditions and predictors for the most common diseases affecting the brain and the spinal cord. This was a retrospective cohort study over a 10-year period in 2 referral institutions using multivariable and multinomial logistic regression for identification of risk factors. In total, 1,140 client-owned dogs diagnosed with inflammatory disease affecting the CNS were included. Fifteen different diagnoses were identified, with immune-mediated (83.6%) disease being more common than infectious conditions (16.4%). The most common immune-mediated conditions diagnosed were meningoencephalitis of unknown origin (47.5%) and steroid-responsive meningitis-arteritis (30.7%), and the most common infectious conditions were discospondylitis (9.3%) and otogenic intracranial infection (2.2%). Older age (
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