Evidence map›Paper›PMID 35155608›Full record

ArticleFrontiers in cardiovascular medicine2021

Association of Body Weight Variability With Progression of Coronary Artery Calcification in Patients With Predialysis Chronic Kidney Disease.

Sang Heon Suh, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Eun Hui Bae, Kook-Hwan Oh, Kyu-Beck Lee, Seung Hyeok Han, Suah Sung, Seong Kwon Ma and 1 more

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Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sang Heon SuhDepartment of Internal Medicine, Chonnam National University Medical School and Chonnam National University Hospital, Gwangju, South Korea.
Tae Ryom OhDepartment of Internal Medicine, Chonnam National University Medical School and Chonnam National University Hospital, Gwangju, South Korea.
Hong Sang ChoiDepartment of Internal Medicine, Chonnam National University Medical School and Chonnam National University Hospital, Gwangju, South Korea.
Chang Seong KimDepartment of Internal Medicine, Chonnam National University Medical School and Chonnam National University Hospital, Gwangju, South Korea.
Eun Hui BaeDepartment of Internal Medicine, Chonnam National University Medical School and Chonnam National University Hospital, Gwangju, South Korea.
Kook-Hwan OhDepartment of Internal Medicine, Seoul National University Hospital, Seoul, South Korea.
Kyu-Beck LeeDepartment of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea.
Seung Hyeok HanDepartment of Internal Medicine, College of Medicine, Institute of Kidney Disease Research, Yonsei University, Seoul, South Korea.
Suah SungDepartment of Internal Medicine, Eulji Medical Center, Eulji University, Seoul, South Korea.
Seong Kwon MaDepartment of Internal Medicine, Chonnam National University Medical School and Chonnam National University Hospital, Gwangju, South Korea.
Soo Wan KimDepartment of Internal Medicine, Chonnam National University Medical School and Chonnam National University Hospital, Gwangju, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe investigated whether high body weight variability (BWV) is associated with a higher prevalence of coronary artery calcification (CAC) or more rapid progression of CAC in patients with predialysis chronic kidney disease (CKD).

methodsA total of 1,162 subjects from a nationwide prospective cohort of predialysis CKD were analyzed. The subjects were divided into the tertile (T1, T2, and T3) by BWV. CAC was assessed at the baseline and a 4-year follow-up by CT scan. Rapid progression of coronary artery calcification was defined as an increase in coronary artery calcium score (CACS) more than 200 Agatston units during a 4-year follow-up.

resultsOne-way ANOVA revealed that CACS change during the follow-up period is significantly higher in the subjects with high BWV, although CACS at the baseline and 4-year follow-up was not different among the tertile groups by BWV. Logistic regression analysis revealed that compared to low BWV (T1), both moderate (T2, adjusted odds ratio (OR) 2.118, 95% CI 1.075-4.175) and high (T3, adjusted OR 2.602, 95% CI 1.304-5.191) BWV was associated with significantly increased risk of rapid progression of CAC. Importantly, the association between BWV and progression of CAC remained robust even among the subjects without significant BW gain or loss during follow-up periods (T2, adjusted OR 2.007, 95% CI 1.011-3.984; T3, adjusted OR 2.054, 95% CI 1.003-4.207).

conclusionHigh BWV is independently associated with rapid progression of CAC in patients with predialysis CKD.

Indexed as

body weigh variabilitycardiovascular diseasecardiovascular eventchronic kidney diseasecoronary artery calcification

Identifiers

PMID35155608
PMCPMC8826058

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