Evidence map›Paper›PMID 35155563›Full record

ArticleFrontiers in molecular biosciences2021

Molecular Architecture of the Antiophidic Protein DM64 and its Binding Specificity to Myotoxin II From

Barbara S Soares, Surza Lucia G Rocha, Viviane A Bastos, Diogo B Lima, Paulo C Carvalho, Fabio C Gozzo, Borries Demeler, Tayler L Williams, Janelle Arnold, Amy Henrickson and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 6 countries.

Barbara S SoaresLaboratory of Toxinology, Oswaldo Cruz Institute, Rio de Janeiro, Brazil.
Surza Lucia G RochaLaboratory of Toxinology, Oswaldo Cruz Institute, Rio de Janeiro, Brazil.
Viviane A BastosLaboratory of Toxinology, Oswaldo Cruz Institute, Rio de Janeiro, Brazil.
Diogo B LimaDepartment of Chemical Biology, Leibniz Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin, Germany.
Paulo C CarvalhoLaboratory for Structural and Computational Proteomics, Carlos Chagas Institute, Curitiba, Brazil.
Fabio C GozzoDalton Mass Spectrometry Laboratory, University of Campinas, Campinas, Brazil.
Borries DemelerDepartment of Biochemistry and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Tayler L WilliamsDepartment of Biochemistry and Structural Biology, University of Texas Health Science Center at San Antonio, San Antonio, TX, United States.
Janelle ArnoldDepartment of Environmental Science, Princeton University, Princeton, NJ, United States.
Amy HenricksonDepartment of Chemistry and Biochemistry, University of Lethbridge, Lethbridge, AB, Canada.
Thomas J D JørgensenDepartment of Biochemistry and Molecular Biology, University of Southern Denmark, Odense, Denmark.
Tatiana A C B SouzaLaboratory for Structural and Computational Proteomics, Carlos Chagas Institute, Curitiba, Brazil.
Jonas PeralesLaboratory of Toxinology, Oswaldo Cruz Institute, Rio de Janeiro, Brazil.
Richard H ValenteLaboratory of Toxinology, Oswaldo Cruz Institute, Rio de Janeiro, Brazil.
Bruno LomonteClodomiro Picado Institute, University of Costa Rica, San José, Costa Rica.
Francisco Gomes-NetoLaboratory of Toxinology, Oswaldo Cruz Institute, Rio de Janeiro, Brazil.
Ana Gisele C Neves-FerreiraLaboratory of Toxinology, Oswaldo Cruz Institute, Rio de Janeiro, Brazil.
Fundação Oswaldo Cruz · BRFundação Carlos Chagas · BRUniversity of Lethbridge · CALeibniz-Forschungsinstitut für Molekulare Pharmakologie · DEPrinceton University · USThe University of Texas Health Science Center at San Antonio · USUniversidad de Costa Rica · CRUniversidade Estadual de Campinas (UNICAMP) · BRUniversity of Southern Denmark · DK

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Lei Zheng · 1991 to 2026
$59.1M
NCI NIH HHS P30 CA054174
6 · The paper itself

Abstract

DM64 is a toxin-neutralizing serum glycoprotein isolated from

Indexed as

antiophidic activitycross-linking (XL)immunoglobulin foldmass spectrometryprotein inhibitorsnake envenomationstructural biologytoxin neutralisation

Identifiers

PMID35155563
PMCPMC8830425
OpenAlexW4210682873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.