Evidence map›Paper›PMID 35155541›Full record

ArticleFrontiers in nutrition2022

A County-Level Spatial Study of Serum Selenoprotein P and Keshan Disease.

Yuehui Jia, Ruixiang Wang, Shengqi Su, Lei Qi, Yuanyuan Wang, Yanan Wang, Yuanjie Zou, Xu Liu, Yiyi Zhang, Jie Hou and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Selenium Status and Its Antioxidant Role in Metabolic Diseases.Oxidative medicine and cellular longevity · 2022
    Review
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Yuehui JiaInstitute of Keshan Disease, Chinese Center for Endemic Disease Control, Harbin Medical University, Harbin, China.
Ruixiang WangInstitute of Keshan Disease, Chinese Center for Endemic Disease Control, Harbin Medical University, Harbin, China.
Shengqi SuInstitute of Keshan Disease, Chinese Center for Endemic Disease Control, Harbin Medical University, Harbin, China.
Lei QiInstitute of Keshan Disease, Chinese Center for Endemic Disease Control, Harbin Medical University, Harbin, China.
Yuanyuan WangInstitute of Keshan Disease, Chinese Center for Endemic Disease Control, Harbin Medical University, Harbin, China.
Yanan WangInstitute of Keshan Disease, Chinese Center for Endemic Disease Control, Harbin Medical University, Harbin, China.
Yuanjie ZouInstitute of Keshan Disease, Chinese Center for Endemic Disease Control, Harbin Medical University, Harbin, China.
Xu LiuInstitute of Keshan Disease, Chinese Center for Endemic Disease Control, Harbin Medical University, Harbin, China.
Yiyi ZhangInstitute of Keshan Disease, Chinese Center for Endemic Disease Control, Harbin Medical University, Harbin, China.
Jie HouInstitute of Keshan Disease, Chinese Center for Endemic Disease Control, Harbin Medical University, Harbin, China.
Hongqi FengInstitute of Keshan Disease, Chinese Center for Endemic Disease Control, Harbin Medical University, Harbin, China.
Qi LiThird Affiliated Hospital of Harbin Medical University, Harbin, China.
Tong WangInstitute of Keshan Disease, Chinese Center for Endemic Disease Control, Harbin Medical University, Harbin, China.
Harbin Medical University · CNBinzhou University · CNYidu Central Hospital of Weifang · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKeshan disease (KD) is strongly associated with selenium deficiency. Selenoprotein P (SELENOP) is a recognized molecular biomarker of selenoproteins and an important indicator of selenium nutrition. This study was aimed at providing geographically precisely visualized evidence of selenium nutrition at molecular level for assessing KD prevention, control, and elimination on the etiological perspective.

methodsWe used spatial ecological design for this study. The serum SELENOP levels of the residents were measured by ELISA. ArcGIS version 9.0 was used for spatial description, spatial autocorrelation analysis of SELENOP levels and spatial regression with per capita disposable income.

resultsThe mean serum SELENOP levels of the 6,382 residents in 1,688 counties were 4.62 ± 1.82 μg/mL. The mean serum SELENOP levels of the residents living in the townships and rural areas of KD endemic counties were not statistically significantly lower than those of the KD non-endemic counties. The mean serum SELENOP levels were globally clustered (Moran's

conclusionsThe results of this study were the geographically precisely visualized evidence of selenium nutrition at molecular level for assessing KD elimination on the etiological perspective. The cold spot counties found by Getis-Ord-Gi

Indexed as

elimination assessmentKeshan diseaseprecision prevention and controlselenoprotein Pspatial epidemiology

Identifiers

PMID35155541
PMCPMC8832143
OpenAlexW4210598951

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.