Evidence map›Paper›PMID 35155528›Full record

ReviewFrontiers in nutrition2021

Mechanisms and Active Compounds Polysaccharides and Bibenzyls of Medicinal Dendrobiums for Diabetes Management.

Mingjian Li, I Gusti Surya Chandra Trapika, Suet Yee Sara Tang, Jun-Lae Cho, Yanfei Qi, Chun Guang Li, Yujuan Li, Meicun Yao, Depo Yang, Bowen Liu and 12 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Review
  3. Quality Evaluation ofPlants (Basel, Switzerland) · 2025
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  5. Effect ofWorld journal of gastroenterology · 2024
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  8. Antioxidants (Basel, Switzerland) · 2024
    Article
  9. Impact of Molecular Weight Variations inFoods (Basel, Switzerland) · 2024
    Article
  10. Review
  11. Review
  12. Foods (Basel, Switzerland) · 2023
    Article
  13. Article
  14. Review
  15. Frontiers in pharmacology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 9 institutions in 4 countries.

Mingjian LiCollege of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
I Gusti Surya Chandra TrapikaFaculty of Medicine and Health, The University of Sydney School of Pharmacy, The University of Sydney, Sydney, NSW, Australia.
Suet Yee Sara TangFaculty of Medicine and Health, The University of Sydney School of Pharmacy, The University of Sydney, Sydney, NSW, Australia.
Jun-Lae ChoFaculty of Medicine and Health, The University of Sydney School of Pharmacy, The University of Sydney, Sydney, NSW, Australia.
Yanfei QiCentenary Institute of Cancer Medicine and Cell Biology, The University of Sydney, Sydney, NSW, Australia.
Chun Guang LiNICM Health Research Institute, Western Sydney University, Penrith, NSW, Australia.
Yujuan LiSchool of Life Science, Beijing Institute of Technology, Beijing, China.
Meicun YaoSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China.
Depo YangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, China.
Bowen LiuSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Rong LiSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Ping YangSchool of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Guoyi MaThe National Center for Natural Products Research, The University of Mississippi, Oxford, MS, United States.
Ping RenInstitute of TCM-related Comorbidity, Nanjing University of Chinese Medicine, Nanjing, China.
Xi HuangInstitute of TCM-related Comorbidity, Nanjing University of Chinese Medicine, Nanjing, China.
Deshan XieChengdu Tepu Biotech Co., Ltd., Chengdu, China.
Shaochao ChenChengdu Tepu Biotech Co., Ltd., Chengdu, China.
Min LiCollege of Fundamental Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Lan YangCollege of Fundamental Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Ping LengCollege of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yong HuangChengdu Tepu Biotech Co., Ltd., Chengdu, China.
George Q LiFaculty of Medicine and Health, The University of Sydney School of Pharmacy, The University of Sydney, Sydney, NSW, Australia.
Chengdu University of Traditional Chinese Medicine · CNNanjing University of Chinese Medicine · CNSun Yat-sen University · CNUniversity of Sydney · AUWestern Sydney University · AUBeijing Institute of Technology · CNCentenary Institute · AUUdayana University · IDUniversity of Mississippi · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMedicinal dendrobiums are used popularly in traditional Chinese medicine for the treatment of diabetes, while their active compounds and mechanism remain unclear. This review aimed to evaluate the mechanism and active compounds of medicinal dendrobiums in diabetes management through a systematic approach.

methodsA systematic approach was conducted to search for the mechanism and active phytochemicals in Dendrobium responsible for anti-diabetic actions using databases PubMed, Embase, and SciFinder.

resultsCurrent literature indicates polysaccharides, bibenzyls, phenanthrene, and alkaloids are commonly isolated in

conclusionPolysaccharides and bibenzyls are the major active compounds in medicinal dendrobiums for diabetic management through the mechanisms of lowering glucose level and reversing chronic inflammation of T2DM by modulating pancreatic β-cell dysfunction and insulin resistance in liver as a result from gut microbita regulation.

Indexed as

active compoundsbibenzylsdendrobiumsdiabetesgut microbiotamechanismpolysaccharides

Identifiers

PMID35155528
PMCPMC8832146
OpenAlexW4210417874

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.