The Prevalence of Depression and Related Factors During the COVID-19 Pandemic Among the General Population of the Jazan Region of Saudi Arabia.

Background This study examines the rates of depression associated with the COVID-19 pandemic along with mitigation measures such as lockdown and quarantine in the population of the Jazan region in Saudi Arabia. The Kingdom of Saudi Arabia (KSA) began mitigation measures before the first case appeared on March 2, 2020, disrupting daily life in a culture that is centered on family life. We sought to assess the psychological impacts of the pandemic on this culturally unique region to see if it affected as many as other reported places in the world. Methods A self-reporting online questionnaire in Arabic was distributed through social media applications and a convenience sample of 942 participants ≥18 years of age living in the Jazan region was selected. The questionnaire included socio-demographics, economic status, chronic medical conditions, focus on and knowledge of COVID-19, and the patient health questionnaire-9 scale (PHQ-9) for depression metrics. The data in this study were analyzed using descriptive analysis of participant characteristics, followed by Chi-square testing to compare reported depression related to each variable. Finally, to control for confounding factors, we applied multivariate logistic regression to find an adjusted odds ratio (AOR) with a 95% CI. Results In the Jazan region, the rate of depression during the COVID-19 pandemic was nearly 26%. There are several significant determinants associated with higher rates of depression in descending order: those with chronic diseases were 160% higher than those without; those with a history of mental illness were 150% higher; participants who focused excessively on the pandemic ≥3 hours daily were 130% higher; participants who were divorced or widowed were 120% higher than singles; females were 87% higher; those under age 40 were 57% higher; students were 50% higher; those reporting low incomes were 40% higher than those with moderate incomes and 60% higher than those with high incomes. Conclusions Strategies need to be devised to protect vulnerable groups of participants from mental health effects, including depression during the COVID-19 pandemic. This will require the collaboration of various institutions, such as schools and others, to provide support for education and mental health. Future research should be aimed at determining the reasons for this higher vulnerability of some groups.