ArticleBiomedical optics express2022
Temperature dependent terahertz spectroscopy and imaging of orthotopic brain gliomas in mouse models.
Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 6 citations in OpenAlex.
- Introduction to the Optics and the Brain 2023 feature issue.Biomedical optics express · 2024Article
- Biomedical application of terahertz imaging technology: a narrative review.Quantitative imaging in medicine and surgery · 2023Review
- Early detection of gastric cancerFrontiers in bioengineering and biotechnology · 2022Article
- A Review of Feasible Applications of THz Waves in Medical Diagnostics and Treatments.Journal of lasers in medical sciences · 2021Review
Corrections and comments
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Terahertz (THz) spectroscopy and imaging were used to differentiate brain gliomas in a mouse model at different temperatures. The THz spectral difference between brain glioma and normal brain tissues at -10°C and 20°C was obtained in the 0.4-2.53 THz range. The absorption coefficient and refractive index values varied with both temperature and frequency. The fresh ex vivo brain glioma tissues were mapped by THz attenuated total reflection (ATR) imaging at 2.52 THz in the temperature range from -20°C to 35°C. Compared with histological examination, THz-ATR imaging could better display the tumor areas at a higher temperature. And the averaged reflectivity of normal tissue was increased with the increase of temperature, whereas the tumor region showed a decreasing trend. Thus, the larger THz imaging difference between glioma and normal tissues could be obtained. Moreover,
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Registered trials
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