Evidence map›Paper›PMID 35154697›Full record

ArticleFood science & nutrition2022

Mulberry (

Xin Zhao, Zhifei Fu, Minghe Yao, Yu Cao, Tongtong Zhu, Rui Mao, Ming Huang, Yafen Pang, Xianghui Meng, Lin Li and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Food science & nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 40 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. mInternational journal of molecular sciences · 2025
    Article
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  6. Article
  7. Article
  8. Review
  9. Review
  10. Frontiers in clinical diabetes and healthcare · 2024
    Review
  11. Food science & nutrition · 2023
    Article
  12. Article
  13. Review
  14. Article
  15. Mulberry (Food science & nutrition · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Xin ZhaoState Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese Medicine Tianjin China.
Zhifei FuState Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese Medicine Tianjin China.
Minghe YaoKey Laboratory of Pharmacology of Traditional Chinese Medical Formula Ministry of Education Tianjin University of Traditional Chinese Medicine Tianjin China.
Yu CaoState Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese Medicine Tianjin China.
Tongtong ZhuState Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese Medicine Tianjin China.
Rui MaoState Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese Medicine Tianjin China.
Ming HuangState Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese Medicine Tianjin China.
Yafen PangState Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese Medicine Tianjin China.
Xianghui MengKey Laboratory of Pharmacology of Traditional Chinese Medical Formula Ministry of Education Tianjin University of Traditional Chinese Medicine Tianjin China.
Lin LiState Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese Medicine Tianjin China.
Boli ZhangState Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese Medicine Tianjin China.
Yuhong LiState Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese Medicine Tianjin China.ORCID https://orcid.org/0000-0002-2358-5449
Han ZhangState Key Laboratory of Component-based Chinese Medicine Tianjin University of Traditional Chinese Medicine Tianjin China.
Tianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary supplements are currently being used to ameliorate metabolic alterations via maintaining gut microflora balance. Mulberry leaf is known as medicine homologous food for its glucose- and lipid-modulating properties. However, the effects of mulberry leaf polysaccharide (MP) on metabolic dysbiosis and gut microbiota are still poorly understood. After extraction and characterization, the beneficial effects of water-soluble MP were evaluated in high-fat diet-induced obese mice. MP treatment could reduce adipose tissue, improve insulin resistance, and alleviate the pathological lesions in colon. Investigation of the underlying mechanism showed that MP modulated gut microbial community by 16S rRNA analysis and reversed the elevation of lipid indexes by plasma lipidomics analysis. Correlation analysis indicated that the abundance of seven key bacterial species and six lipids were closely associated with the metabolic traits, respectively. Overall, MP could ameliorate metabolic disorders, and modify the gut microbiota and lipids. This would greatly facilitate the utilization of MP as a functional food.

Indexed as

gut microbiotainsulin resistancelipidsmetabolic disordermulberry leaf polysaccharideobesity

Identifiers

PMID35154697
PMCPMC8825736
OpenAlexW4200088151

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.