Evidence map›Paper›PMID 35154606›Full record

ArticleGastroenterology and hepatology from bed to bench2021

High viral load detection of human Cosavirus in Iranian pediatric patients with acute gastroenteritis.

Sadaf Khoshbazan, Zahra Ivani, Seyed Dawood Mousavi Nasab, Nayebali Ahmadi, Aynaz Parhiz, Bahman Khalesi, Mohammad Hassan Firouzjani, Mostafa Ghaderi, Maryam Barati, Mohammad Javad Ehsani Ardakani

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Article in Gastroenterology and hepatology from bed to bench, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 54% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Sadaf KhoshbazanDepartment of Microbiology, Karaj Branch, Islamic Azad University, Karaj, Iran.
Zahra IvaniDepartment of Animal Viral Vaccine, Razi Vaccine and Serum Research Institute (RVSRI), Agricultural Research, Education and Extension Organization (AREEO) Karaj, Iran.
Seyed Dawood Mousavi NasabDepartment of Research and Development, Production and Research Complex, Pasteur Institute of Iran, Tehran, Iran.
Nayebali AhmadiProteomics Research Center, Department of Medical Laboratory Sciences, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Aynaz ParhizDepartment of Microbiology, Karaj Branch, Islamic Azad University, Karaj, Iran.
Bahman KhalesiDepartment of Research and Production of Poultry Viral Vaccine, Razi Vaccine and Serum Research Institute, Agricultural Research Education and Extension Organization (AREEO), Karaj, Iran.
Mohammad Hassan FirouzjaniDepartment of Therapeutic Sera Quality Control, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organisation (AREEO), Karaj, Iran.
Mostafa GhaderiDepartment of Microbiology, Karaj Branch, Islamic Azad University, Karaj, Iran.
Maryam BaratiLaser Application in Medical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mohammad Javad Ehsani ArdakaniGastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Islamic Azad University, Karaj · IRShahid Beheshti University of Medical Sciences · IRAgricultural Research & Education Organization · IRPasteur Institute of Iran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe present study implemented an RT-qPCR assay for the detection and quantification of human cosavirus in stool specimens from pediatric patients involved in acute gastroenteritis.

backgroundHuman cosavirus is a newly recognized virus that seems to be partly related to acute gastroenteritis in pediatric patients. However, the relationship between human cosavirus and diseases in humans is unclear.

methodsFrom January 2018 to December 2019, a total of 160 stool samples were collected from pediatric patients presenting with acute gastroenteritis in a hospital in Karaj, Iran. After viral RNA extraction, RT-qPCR was performed to amplify the 5'UTR region of the human cosavirus genome and viral load was analyzed.

resultsThe human cosavirus genomic RNA was detected in 4/160 (2.5%) stool samples tested. The maximum viral load was determined to be 4.6×10

conclusionThe human cosavirus as a new member of the Picornaviridae family was illustrated in fecal samples from pediatric patients with acute gastroenteritis in Iran. This is the first documentation of human cosavirus circulation in Iranian children.

Indexed as

Acute gastroenteritisCosavirusPediatric PatientsStool

Identifiers

PMID35154606
PMCPMC8817751
OpenAlexW4213393085

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.