Evidence map›Paper›PMID 35154496›Full record

ArticleTheranostics2022

Ginger nanoparticles mediated induction of Foxa2 prevents high-fat diet-induced insulin resistance.

Anil Kumar, Kumaran Sundaram, Yun Teng, Jingyao Mu, Mukesh K Sriwastva, Lifeng Zhang, Joshua L Hood, Jun Yan, Xiang Zhang, Juw Won Park and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.

  1. Pooled it
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  18. Terpenoid-enrichedExtracellular vesicles and circulating nucleic acids · 2026
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Anil KumarJames Graham Brown Cancer Center, Department of Microbiology & Immunology, University of Louisville, KY 40202, USA.
Kumaran SundaramJames Graham Brown Cancer Center, Department of Microbiology & Immunology, University of Louisville, KY 40202, USA.
Yun TengJames Graham Brown Cancer Center, Department of Microbiology & Immunology, University of Louisville, KY 40202, USA.
Jingyao MuJames Graham Brown Cancer Center, Department of Microbiology & Immunology, University of Louisville, KY 40202, USA.
Mukesh K SriwastvaJames Graham Brown Cancer Center, Department of Microbiology & Immunology, University of Louisville, KY 40202, USA.
Lifeng ZhangJames Graham Brown Cancer Center, Department of Microbiology & Immunology, University of Louisville, KY 40202, USA.
Joshua L HoodDepartment of Pharmacology and Toxicology, University of Louisville, Louisville, KY40202, USA.
Jun YanJames Graham Brown Cancer Center, Department of Microbiology & Immunology, University of Louisville, KY 40202, USA.
Xiang ZhangDepartment of Pharmacology and Toxicology, University of Louisville, Louisville, KY40202, USA.
Juw Won ParkDepartment of Computer Engineering and Computer Science, University of Louisville, KY40202, USA.
Michael L MerchantKidney Disease Program and Clinical Proteomics Center, University of Louisville, Louisville, KY, USA.
Huang-Ge ZhangJames Graham Brown Cancer Center, Department of Microbiology & Immunology, University of Louisville, KY 40202, USA.
University of Louisville · USLouisville VA Medical Center · US

Funding

WKU Lead Faculty AwardP20GM103436 · NIGMS · UNIVERSITY OF LOUISVILLE · PI ERIC C ROUCHKA · 2012 to 2026
$60.1M
Understanding the Host-Microbiome-Therapeutic Triad: Implications for Designing Alternative IntravaginalP20GM125504 · NIGMS · UNIVERSITY OF LOUISVILLE · PI Shirin Ghods · 2018 to 2026
$24.4M
Role of oxidized linoleic acid metabolites in the pathogenesis of alcoholic liver diseaseP20GM113226 · NIGMS · UNIVERSITY OF LOUISVILLE · PI MCCLAIN, CRAIG J. · 2016 to 2025
$24.1M
The Role of Nutrition in the Development/Progression of Alcohol-Induced Organ InjuryP50AA024337 · NIAAA · UNIVERSITY OF LOUISVILLE · PI CRAIG J. MCCLAIN · 2016 to 2026
$17.9M
Plant exosomes non-coding RNA-mediated anti-inflammatory mechanismsR01AT008617 · NCCIH · UNIVERSITY OF LOUISVILLE · PI HUANG-GE ZHANG · 2016 to 2026
$5.7M
Mechanisms of Probiotics in Alcoholic Liver DiseaseR01AA023190 · NIAAA · UNIVERSITY OF LOUISVILLE · PI FENG, WENKE · 2015 to 2024
$3.5M
NCCIH NIH HHS R01 AT008617NIAAA NIH HHS P50 AA024337NIAAA NIH HHS R01 AA023190NIGMS NIH HHS P20 GM103436NIGMS NIH HHS P20 GM113226NIGMS NIH HHS P20 GM125504
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Diabetes Mellitus, Type 2Insulin ResistanceNanoparticlesZingiber officinaleAnimalsDiet, High-FatHepatocyte Nuclear Factor 3-betaLiposomesMiceMice, Inbred C57BLObesityProto-Oncogene Proteins c-aktFoxa2 protein, mouseHepatocyte Nuclear Factor 3-betaLipid NanoparticlesLiposomesProto-Oncogene Proteins c-aktexosomesFoxa2Ginger-derived nanoparticlesinsulin resistancelifespanphosphatidic acidskin inflammation

Identifiers

PMID35154496
PMCPMC8771553
OpenAlexW4206548975

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.