Evidence map›Paper›PMID 35154485›Full record

ArticleTheranostics2022

Engineered extracellular vesicle-based sonotheranostics for dual stimuli-sensitive drug release and photoacoustic imaging-guided chemo-sonodynamic cancer therapy.

Thuy Giang Nguyen Cao, Ji Hee Kang, Wangyu Kim, Junha Lim, Su Jin Kang, Jae Young You, Quan Truong Hoang, Won Jong Kim, Won Jong Rhee, Chulhong Kim and 2 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 93 citations in OpenAlex.

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  19. Hollow RuOTheranostics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Thuy Giang Nguyen CaoDivision of Bioengineering, Incheon National University, Incheon 22012, Republic of Korea.
Ji Hee KangCollege of Pharmacy, Gachon University, Incheon 21936, Republic of Korea.
Wangyu KimDepartment of Electrical Engineering, Convergence IT Engineering, and Mechanical Engineering, Medical Device Innovation Center, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.
Junha LimDepartment of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.
Su Jin KangDivision of Bioengineering, Incheon National University, Incheon 22012, Republic of Korea.
Jae Young YouDivision of Bioengineering, Incheon National University, Incheon 22012, Republic of Korea.
Quan Truong HoangDivision of Bioengineering, Incheon National University, Incheon 22012, Republic of Korea.
Won Jong KimDepartment of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.
Won Jong RheeDivision of Bioengineering, Incheon National University, Incheon 22012, Republic of Korea.
Chulhong KimDepartment of Electrical Engineering, Convergence IT Engineering, and Mechanical Engineering, Medical Device Innovation Center, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea.
Young Tag KoCollege of Pharmacy, Gachon University, Incheon 21936, Republic of Korea.
Min Suk ShimDivision of Bioengineering, Incheon National University, Incheon 22012, Republic of Korea.
Incheon National University · KRPohang University of Science and Technology · KRGachon University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sonodynamic therapy has shown promise as an effective alternative to conventional photodynamic therapy owing to its ability to treat deep-seated tumors. However, the development of stimuli-responsive sonosensitizers with high biocompatibility faces a significant challenge.

Indexed as

Extracellular VesiclesNanoparticlesNeoplasmsPhotoacoustic TechniquesAnimalsCell Line, TumorDrug LiberationHumansIndocyanine GreenMicePaclitaxelIndocyanine GreenPaclitaxelextracellular vesiclephotoacoustic imagingpH-sensitive releasesonodynamic cancer therapysonotheranostics

Identifiers

PMID35154485
PMCPMC8771566
OpenAlexW4206273256

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.