Evidence map›Paper›PMID 35154387›Full record

ArticleTherapeutic advances in gastroenterology2021

Endoscopic management of anastomotic leak after esophageal or gastric resection for malignancy: a multicenter experience.

Rachel Hallit, Mélanie Calmels, Ulriikka Chaput, Diane Lorenzo, Aymeric Becq, Marine Camus, Xavier Dray, Jean Michel Gonzalez, Marc Barthet, Jérémie Jacques and 9 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutic advances in gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 5 institutions in 1 country.

Rachel HallitDepartment of Gastroenterology, Cochin Hospital, Assistance Publique-Hôpitaux de Paris and University of Paris, 27, rue du Faubourg St Jacques, Paris, 75014, France.ORCID https://orcid.org/0000-0001-8866-6234
Mélanie CalmelsDigestive Surgery Department, St Louis University Hospital, Assistance Publique Hôpitaux de Paris and University of Paris, Paris, France.
Ulriikka ChaputSorbonne University, Endoscopy Unit, AP-HP, Hôpital Saint-Antoine, Paris, France.
Diane LorenzoGastroenterology Department, Beaujon University Hospital, Assistance Publique-Hôpitaux de Paris and University of Paris, Paris, France.
Aymeric BecqSorbonne University, Endoscopy Unit, AP-HP, Hôpital Saint-Antoine, Paris, France.
Marine CamusSorbonne University, Endoscopy Unit, AP-HP, Hôpital Saint-Antoine, Paris, France.ORCID https://orcid.org/0000-0003-2566-3866
Xavier DraySorbonne University, Endoscopy Unit, AP-HP, Hôpital Saint-Antoine, Paris, France.
Jean Michel GonzalezGastroenterology Department, North Hospital, Assistance Publique - Hôpitaux de Marseille and University of Aix-Marseille, Marseille, France.
Marc BarthetGastroenterology Department, North Hospital, Assistance Publique - Hôpitaux de Marseille and University of Aix-Marseille, Marseille, France.
Jérémie JacquesGastroenterology Department, Limoges University Hospital, and University Limoges, Limoges, France.
Thierry BarriozGastroenterology Department, Poitiers University Hospital, Poitiers, France.
Romain LegrosGastroenterology Department, Limoges University Hospital, and University Limoges, Limoges, France.
Arthur BelleGastroenterology Department, Cochin University Hospital, Assistance Publique-Hôpitaux de Paris and University of Paris, Paris, France.
Stanislas ChaussadeGastroenterology Department, Cochin University Hospital, Assistance Publique-Hôpitaux de Paris and University of Paris, Paris, France.
Romain CoriatGastroenterology Department, Cochin University Hospital, Assistance Publique-Hôpitaux de Paris and University of Paris, Paris, France.
Pierre CattanDigestive Surgery Department, St Louis University Hospital, Assistance Publique Hôpitaux de Paris and University of Paris, Paris, France.
Frédéric PratGastroenterology Department, Cochin University Hospital, Assistance Publique-Hôpitaux de Paris and University of Paris, Paris, France.
Diane GoereDigestive Surgery Department, St Louis University Hospital, Assistance Publique Hôpitaux de Paris and University of Paris, Paris, France.
Maximilien BarretGastroenterology Department, Cochin University Hospital, Assistance Publique-Hôpitaux de Paris and University of Paris, Paris, France.
Université Paris Cité · FRSorbonne Université · FRAssistance Publique Hôpitaux de Marseille · FRUniversité de Limoges · FRUniversité de Poitiers · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMost anastomotic leaks after surgical resection for esophageal or esophagogastric junction malignancies are treated endoscopically with esophageal stents. Internal drainage by double pigtail stents has been used for the endoscopic management of leaks following bariatric surgery, and recently introduced for anastomotic leaks after resections for malignancies. Our aim was to assess the overall efficacy of the endoscopic treatment for anastomotic leaks after esophageal or gastric resection for malignancies.

methodsWe conducted a multicenter retrospective study in four digestive endoscopy tertiary referral centers in France. We included consecutive patients managed endoscopically for anastomotic leak following esophagectomy or gastrectomy for malignancies between January 2016 and December 2018. The primary outcome was the efficacy of the endoscopic management on leak closure.

resultsSixty-eight patients were included, among which 46 men and 22 women, with a mean ± SD age of 61 ± 11 years. Forty-four percent had an Ivor Lewis procedure, 16% a tri-incisional esophagectomy, and 40% a total gastrectomy. The median time between surgery and the diagnosis of leak was 9 (6-13) days. Endoscopic treatment was successful in 90% of the patients. The efficacy of internal drainage and esophageal stents was 95% and 77%, respectively (

conclusionEndoscopic management of early postoperative leak is successful in 90% of patients, preventing highly morbid surgical revisions. Internal endoscopic drainage should be considered as the first-line endoscopic treatment of anastomotic fistulas whenever technically feasible.

Indexed as

anastomotic leakdouble pigtail stentendoscopic managementesophageal canceresophageal or gastric canceresophagogastric junction adenocarcinomagastric cancerinternal drainageself-expendable metallic stent

Identifiers

PMID35154387
PMCPMC8832292
OpenAlexW3185067784

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.