Evidence map›Paper›PMID 35154076›Full record

ArticleFrontiers in immunology2021

A Comprehensive Evaluation of the Antibody-Verified Status of Eplets Listed in the HLA Epitope Registry.

Suzanne Bezstarosti, Kim H Bakker, Cynthia S M Kramer, Johan W de Fijter, Marlies E J Reinders, Arend Mulder, Frans H J Claas, Sebastiaan Heidt

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 56 citations in OpenAlex.

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  14. The Progress and Challenges of Implementing HLA Molecular Matching in Clinical Practice.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Review
  15. Review
  16. Frontiers in immunology · 2025
    Article
  17. Article
  18. Review
  19. Early progression of chronic histologic lesions in kidney transplant biopsies is not associated with HLA histocompatibility.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2024
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Suzanne BezstarostiDepartment of Immunology, Leiden University Medical Center, Leiden, Netherlands.
Kim H BakkerDepartment of Immunology, Leiden University Medical Center, Leiden, Netherlands.
Cynthia S M KramerDepartment of Immunology, Leiden University Medical Center, Leiden, Netherlands.
Johan W de FijterDepartment of Internal Medicine (Nephrology), Leiden University Medical Center, Leiden, Netherlands.
Marlies E J ReindersDepartment of Internal Medicine, Erasmus Medical Center Transplantation Institute, University Medical Center Rotterdam, Rotterdam, Netherlands.
Arend MulderDepartment of Immunology, Leiden University Medical Center, Leiden, Netherlands.
Frans H J ClaasDepartment of Immunology, Leiden University Medical Center, Leiden, Netherlands.
Sebastiaan HeidtDepartment of Immunology, Leiden University Medical Center, Leiden, Netherlands.
Leiden University Medical Center · NLErasmus MC · NLEurotransplant · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Matching strategies based on HLA eplets instead of HLA antigens in solid organ transplantation may not only increase the donor pool for highly sensitized patients, but also decrease the incidence of

Indexed as

AllelesAmino Acid SequenceAntibodies, MonoclonalDatabases, GeneticEpitopesHistocompatibilityHistocompatibility TestingHLA AntigensHumansIsoantibodiesModels, MolecularRegistriesStructure-Activity RelationshipTransplantationAntibodies, MonoclonalEpitopesHLA AntigensIsoantibodiesantibody verificationepitope-matchingeplethuman leukocyte antigenmonoclonal antibodyreactivity patterntransplantation

Identifiers

PMID35154076
PMCPMC8831796
OpenAlexW4210392069

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.