Evidence map›Paper›PMID 35153978›Full record

ArticleFrontiers in neurology2021

A Case Series and Literature Review of Vertebral Artery Stump Syndrome.

Wenbin Zhang, Shouchun Wang, Chao Li, Zhongxiu Wang, Feixue Yue, Jie Zhou, Kangjia Song, Chao Wang, Yujiao Wang, Mingchao Shi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Wenbin ZhangDepartment of Neurology, The First Bethune Hospital of Jilin University, Jilin University, Changchun, China.
Shouchun WangDepartment of Neurology, The First Bethune Hospital of Jilin University, Jilin University, Changchun, China.
Chao LiDepartment of Neurology, The First Bethune Hospital of Jilin University, Jilin University, Changchun, China.
Zhongxiu WangDepartment of Neurology, The First Bethune Hospital of Jilin University, Jilin University, Changchun, China.
Feixue YueDepartment of Neurology, The First Bethune Hospital of Jilin University, Jilin University, Changchun, China.
Jie ZhouDepartment of Neurology, The First Bethune Hospital of Jilin University, Jilin University, Changchun, China.
Kangjia SongDepartment of Neurology, The First Bethune Hospital of Jilin University, Jilin University, Changchun, China.
Chao WangDepartment of Neurology, The First Bethune Hospital of Jilin University, Jilin University, Changchun, China.
Yujiao WangNursing Department, The First Bethune Hospital of Jilin University, Jilin University, Changchun, China.
Mingchao ShiDepartment of Neurology, The First Bethune Hospital of Jilin University, Jilin University, Changchun, China.
First Bethune Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeStump syndrome refers to cerebral ischaemic symptoms caused by an embolus from a previously occluded ipsilateral artery that occludes a down-stream artery. It can be divided into two types: carotid stump syndrome and vertebral artery stump syndrome (VASS). At present, there is limited clinical experience with VASS. We aimed to propose a more precise diagnostic standard for VASS, and to share our experience with handling this condition. MATERIALS AND

methodsWe retrospectively collected data of patients who were treated with endovascular thrombectomy in the stroke centre of the First Hospital of Jilin University from January 2016 to March 2020. After screening patients with posterior-circulation acute ischaemic stroke, we selected patients who had an acute occlusion of an intracranial artery in the context of a previously occluded ipsilateral vertebral artery origin, as confirmed by digital subtraction angiography.

resultsEleven patients met our inclusion criteria. Nine patients achieved recanalization of both extracranial and intracranial occluded arteries, one patient had modified thrombolysis in cerebral infarction grade 3, and eight patients had grade 2b. Residual stenosis of recanalized intracranial arteries was less than 30% in all cases, while three patients had embolism of distal arteries. No dissection or subarachnoid haemorrhage occurred. Two patients didn't reach vascular recanalization. Among the nine patients with recanalized artery, four had a 90-day modified Rankin Scale score ≤ 3 (favourable outcome), and four patients died; As for the two non-recanalized patients, one had a mRS score of 5 and one died.

conclusionVASS is a clinical syndrome caused by embolic occlusion of a distal intracranial artery occluded ipsilateral extracranial vertebral artery. Antegrade blood flow from the collateral vessels, distal embolic occlusion and mild or no residual stenosis of the occluded intracranial artery after recanalization are notable features of this clinical event. Endovascular thrombectomy may be effective for treating VASS.

Indexed as

diagnosisendovascular thrombectomytandem lesionstherapyvertebral artery stump syndrome

Identifiers

PMID35153978
PMCPMC8831726
OpenAlexW4210639659

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.