Evidence map›Paper›PMID 35153759›Full record

ArticleFrontiers in pharmacology2021

Magnesium-Assisted Cisplatin Inhibits Bladder Cancer Cell Survival by Modulating Wnt/β-Catenin Signaling Pathway.

Tianye Li, Zihan Tang, Chunting Li, Xiaoya Liu, Linglin Cheng, Zhijing Yang, Xiaojin Zhu, Weiwei Liu, Yongye Huang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tianye LiCollege of Life and Health Sciences, Northeastern University, Shenyang, China.
Zihan TangCollege of Life and Health Sciences, Northeastern University, Shenyang, China.
Chunting LiCollege of Life and Health Sciences, Northeastern University, Shenyang, China.
Xiaoya LiuCollege of Life and Health Sciences, Northeastern University, Shenyang, China.
Linglin ChengCollege of Life and Health Sciences, Northeastern University, Shenyang, China.
Zhijing YangDepartment of Oral and Maxillofacia Surgery, Hospital of Stomatology, Jilin University, Changchun, China.
Xiaojin ZhuCollege of Life and Health Sciences, Northeastern University, Shenyang, China.
Weiwei LiuDepartment of Oral and Maxillofacia Surgery, Hospital of Stomatology, Jilin University, Changchun, China.
Yongye HuangCollege of Life and Health Sciences, Northeastern University, Shenyang, China.
Northeastern University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnesium, an essential mineral micronutrient, plays a role in the activation of various transporters and enzymes. The present study aimed to investigate the possibility of applying magnesium to enhance the efficacy of cisplatin which is still ranked as one of the major chemotherapeutic drugs for bladder cancer patients. Results showed that the survival rate and colony formation of bladder cancer cells were reduced by combinatorial treatment with cisplatin and magnesium chloride (MgCl

Indexed as

autophagycancercisplatinmagnesiumβ-catenin

Identifiers

PMID35153759
PMCPMC8829071
OpenAlexW4210520294

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.