Evidence map›Paper›PMID 35153714›Full record

SynthesisFrontiers in aging neuroscience2021

Prevalence and Associated Risk Factors of Cognitive Frailty: A Systematic Review and Meta-Analysis.

Tao Zhang, Yan Ren, Ping Shen, Shixie Jiang, Yanrong Yang, Yan Wang, Zheng Li, Ying Yang

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Frontiers in aging neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 8 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tao ZhangSchool of Medicine, Zunyi Medical University, Zunyi, China.
Yan RenDepartment of Geriatrics, Fifth People's Hospital of Chengdu, Chengdu, China.
Ping ShenCollege of Life and Science, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Shixie JiangDepartment of Psychiatry and Behavioral Neurosciences, University of South Florida, Tampa, FL, United States.
Yanrong YangDepartment of Neurology, Fifth People's Hospital of Chengdu, Chengdu, China.
Yan WangDepartment of Neurology, Fifth People's Hospital of Chengdu, Chengdu, China.
Zheng LiDepartment of Neurology, Fifth People's Hospital of Chengdu, Chengdu, China.
Ying YangDepartment of Neurology, Fifth People's Hospital of Chengdu, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCurrently, the prevalence of CF (Cognitive Frailty) is not very clear, and the relationship between CF and its associated risk factors has not been accurately evaluated. Therefore, it is necessary to conduct a systematic review and meta-analysis further to understand CF's prevalence and associated factors.

methodsEmbase, PubMed, Web of Science, Ovid, and Cochrane were systematically searched for articles exploring the prevalence of CF, the deadline of searching date was up to March 2021. For the prevalence of CF, the events of CF and the total number of patients in every included study were extracted to estimate the prevalence of CF. For associated factors of CF, Odds Ratios (ORs) with (corresponding) 95% confidence intervals (CIs) were used for estimations.

resultsFirstly, the estimated prevalence of CF I (Cognitive Frailty in the model I) was 16%, 95% CI (0.13-0.19), and the estimated prevalence of CF II (Cognitive Frailty in model II) was 6%, 95% CI (0.05-0.07). Secondly, both lower engagement in activities and age were calculated to be independent risk factors of CF, and the OR (95% CI) was 3.31 (2.28-4.81) and 1.10 (1.04-1.16), respectively. Finally, depression was also a prominent risk factor of CF, with the overall OR (95% CI) as 1.57 (1.32-1.87).

conclusionCF was a high prevalence in community older. The various assessment scales and the different cutoff values of diagnostic criteria would affect the prevalence of CF. Lower engagement in activities, age, and depression was the risky factor of CF. SYSTEMATIC REVIEW REGISTRATION: http://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42019121369.

Indexed as

associated factorcognitivecognitive frailty (CF)frailtyprevalence

Identifiers

PMID35153714
PMCPMC8832102

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.