Evidence map›Paper›PMID 35153679›Full record

ArticleFrontiers in neural circuits2021

The Long and Winding Road-Vestibular Efferent Anatomy in Mice.

David Lorincz, Lauren A Poppi, Joseph C Holt, Hannah R Drury, Rebecca Lim, Alan M Brichta

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neural circuits, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Molecular and Functional Changes to Postsynaptic Cholinergic Signaling in the Vestibular Sensory Organs of Aging C57BL/6 Mice.The journals of gerontology. Series A, Biological sciences and medical sciences · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

David LorinczSchool of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia.
Lauren A PoppiSchool of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia.
Joseph C HoltDepartment of Otolaryngology, University of Rochester, Rochester, NY, United States.
Hannah R DrurySchool of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia.
Rebecca LimSchool of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia.
Alan M BrichtaSchool of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, NSW, Australia.
University of Newcastle Australia · AUUniversity of Rochester · US

Funding

Synaptic Mechanisms of Mammalian Vestibular Efferent ResponsesR01DC016974 · NIDCD · UNIVERSITY OF ROCHESTER · PI HOLT, JOSEPH CHRISTOPHER · 2018 to 2022
$1.6M
NIDCD NIH HHS R01 DC016974
6 · The paper itself

Abstract

The precise functional role of the Efferent Vestibular System (EVS) is still unclear, but the auditory olivocochlear efferent system has served as a reasonable model on the effects of a cholinergic and peptidergic input on inner ear organs. However, it is important to appreciate the similarities and differences in the structure of the two efferent systems, especially within the same animal model. Here, we examine the anatomy of the mouse EVS, from its central origin in the Efferent Vestibular Nucleus (EVN) of the brainstem, to its peripheral terminations in the vestibular organs, and we compare these findings to known mouse olivocochlear anatomy. Using transgenic mouse lines and two different tracing strategies, we examine

Indexed as

Neurons, EfferentVestibule, LabyrinthAnimalsBrain StemEfferent PathwaysMammalsMiceNeuronsVestibular Nucleianterogradecre-dependentefferentsmouseretrogradevestibular

Identifiers

PMID35153679
PMCPMC8832101
OpenAlexW4210760132

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.