Evidence map›Paper›PMID 35153677›Full record

ArticleFrontiers in neural circuits2021

Delays in the Reticulospinal System Are Associated With a Reduced Capacity to Learn a Simulated Feeding Task in Older Adults.

Vishvak Rangarajan, Joseph J Schreiber, Beatriz Barragan, Sydney Y Schaefer, Claire F Honeycutt

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neural circuits, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vishvak RangarajanSchool of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, United States.
Joseph J SchreiberSchool of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, United States.
Beatriz BarraganSchool of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, United States.
Sydney Y SchaeferSchool of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, United States.
Claire F HoneycuttSchool of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ, United States.
Arizona State University · US

Funding

Generalization of functional task-specific motor training in older adultsK01AG047926 · NIA · UTAH STATE UNIVERSITY · PI SCHAEFER, SYDNEY YOSHIE · 2015 to 2018
$543k
NIA NIH HHS K01 AG047926
6 · The paper itself

Abstract

Learning declines with age. Recent evidence indicates that the brainstem may play an important role in learning and motor skill acquisition. Our objective was to determine if delays in the reticular formation, measured via the startle reflex, correspond to age-related deficits in learning and retention. We hypothesized that delays in the startle reflex would be linearly correlated to learning and retention deficits in older adults. To determine if associations were unique to the reticulospinal system, we also evaluated corticospinal contributions with transcranial magnetic stimulation. Our results showed a linear relationship between startle onset latency and percent learning and retention but no relationship between active or passive motor-evoked potential onsets or peak-to-peak amplitude. These results lay the foundation for further study to evaluate if (1) the reticular formation is a subcortical facilitator of skill acquisition and (2) processing delays in the reticular formation contribute to age-related learning deficits.

Indexed as

Evoked Potentials, MotorTranscranial Magnetic StimulationLearningReflex, StartleReticular Formationagingbrainstemlearningmotor learningreticular formationreticulospinalskill acquisitionstartle

Identifiers

PMID35153677
PMCPMC8829385
OpenAlexW4210612298

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.