Evidence map›Paper›PMID 35153670›Full record

ArticleFrontiers in molecular neuroscience2021

An

Peter Deng, Julian A N M Halmai, Ulrika Beitnere, David Cameron, Michele L Martinez, Charles C Lee, Jennifer J Waldo, Krista Thongphanh, Anna Adhikari, Nycole Copping and 15 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Epigenetic editing: from concept to clinic.Nature reviews. Drug discovery · 2026
    Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 1 institution in 1 country.

Peter DengDepartment of Neurology, University of California Davis School of Medicine, Sacramento, CA, United States.
Julian A N M HalmaiDepartment of Neurology, University of California Davis School of Medicine, Sacramento, CA, United States.
Ulrika BeitnereDepartment of Biochemistry and Molecular Medicine, Genome Center, University of California, Davis, Davis, CA, United States.
David CameronDepartment of Neurology, University of California Davis School of Medicine, Sacramento, CA, United States.
Michele L MartinezDepartments of Pediatrics and Cell Biology and Human Anatomy, School of Medicine, Gene Therapy Center, and California National Primate Research Center, University of California, Davis, Davis, CA, United States.
Charles C LeeDepartments of Pediatrics and Cell Biology and Human Anatomy, School of Medicine, Gene Therapy Center, and California National Primate Research Center, University of California, Davis, Davis, CA, United States.
Jennifer J WaldoDepartment of Neurology, University of California Davis School of Medicine, Sacramento, CA, United States.
Krista ThongphanhDepartment of Neurology, University of California Davis School of Medicine, Sacramento, CA, United States.
Anna AdhikariDepartment of Psychiatry and Behavioral Sciences, MIND Institute, University of California Davis School of Medicine, Sacramento, CA, United States.
Nycole CoppingDepartment of Psychiatry and Behavioral Sciences, MIND Institute, University of California Davis School of Medicine, Sacramento, CA, United States.
Stela P PetkovaDepartment of Psychiatry and Behavioral Sciences, MIND Institute, University of California Davis School of Medicine, Sacramento, CA, United States.
Ruth D LeeDepartment of Psychiatry and Behavioral Sciences, MIND Institute, University of California Davis School of Medicine, Sacramento, CA, United States.
Samantha LockDepartment of Neurology, University of California Davis School of Medicine, Sacramento, CA, United States.
Miranda PalomaresDepartment of Biochemistry and Molecular Medicine, Genome Center, University of California, Davis, Davis, CA, United States.
Henriette O'GeenDepartment of Biochemistry and Molecular Medicine, Genome Center, University of California, Davis, Davis, CA, United States.
Jasmine CarterDepartment of Neurology, University of California Davis School of Medicine, Sacramento, CA, United States.
Casiana E GonzalezDepartment of Neurology, University of California Davis School of Medicine, Sacramento, CA, United States.
Fiona K B BuchananDepartment of Neurology, University of California Davis School of Medicine, Sacramento, CA, United States.
Johnathan D AndersonDepartment of Otolaryngology, University of California, Davis, Davis, CA, United States.
Fernando A FierroStem Cell Program and Gene Therapy Center, University of California, Davis, Sacramento, CA, United States.
Jan A NoltaStem Cell Program and Gene Therapy Center, University of California, Davis, Sacramento, CA, United States.
Alice F TarantalDepartments of Pediatrics and Cell Biology and Human Anatomy, School of Medicine, Gene Therapy Center, and California National Primate Research Center, University of California, Davis, Davis, CA, United States.
Jill L SilvermanDepartment of Psychiatry and Behavioral Sciences, MIND Institute, University of California Davis School of Medicine, Sacramento, CA, United States.
David J SegalDepartment of Biochemistry and Molecular Medicine, Genome Center, University of California, Davis, Davis, CA, United States.
Kyle D FinkDepartment of Neurology, University of California Davis School of Medicine, Sacramento, CA, United States.
University of California, Davis · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
Institutional Career Development Core (KL2)KL2TR001859 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI HOLMES, JAMES F. · 2016 to 2025
$10.1M
UC Davis CTSC TL1 Administrative Supplement to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility MentorshipTL1TR001861 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MEDICI, VALENTINA · 2016 to 2025
$4.7M
Learning, Memory, and Plasticity (LaMP) Training ProgramT32MH112507 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Karen Zito · 2017 to 2026
$2.4M
NCATS NIH HHS KL2 TR001859NCATS NIH HHS TL1 TR001861NCATS NIH HHS UL1 TR001860NIMH NIH HHS T32 MH112507
6 · The paper itself

Abstract

Zinc finger (ZF), transcription activator-like effectors (TALE), and CRISPR/Cas9 therapies to regulate gene expression are becoming viable strategies to treat genetic disorders, although effective

Indexed as

Angelman Syndrome (AS)artificial transcription factor (ATF)cell-based deliverymesenchymal stem/stromal cellzinc finger

Identifiers

PMID35153670
PMCPMC8829036
OpenAlexW4210371286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.