Evidence map›Paper›PMID 35153497›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2022

The Association Between Fecal Short-Chain Fatty Acids, Gut Microbiota, and Visceral Fat in Monozygotic Twin Pairs.

Xing-Qi Yin, Ya-Xin An, Cai-Guo Yu, Jing Ke, Dong Zhao, Ke Yu

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  4. Dragon Fruit Peel (Antioxidants (Basel, Switzerland) · 2025
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  6. Observational
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  15. The administration ofFrontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Xing-Qi Yin *Center for Endocrine Metabolism and Immune Diseases, Luhe Hospital, Capital Medical University, Beijing, People's Republic of China.
Ya-Xin An *Center for Endocrine Metabolism and Immune Diseases, Luhe Hospital, Capital Medical University, Beijing, People's Republic of China.
Cai-Guo YuCenter for Endocrine Metabolism and Immune Diseases, Luhe Hospital, Capital Medical University, Beijing, People's Republic of China.
Jing KeCenter for Endocrine Metabolism and Immune Diseases, Luhe Hospital, Capital Medical University, Beijing, People's Republic of China.
Dong ZhaoCenter for Endocrine Metabolism and Immune Diseases, Luhe Hospital, Capital Medical University, Beijing, People's Republic of China.
Ke YuCenter for Endocrine Metabolism and Immune Diseases, Luhe Hospital, Capital Medical University, Beijing, People's Republic of China.
Beijing Luhe Hospital Affiliated to Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo examine the association of short-chain fatty acids (SCFAs), gut microbiota and obesity in individual twins and to control for genetic and shared environmental effects by studying monozygotic intrapair differences. PATIENTS AND

methodsThe study recruited 20 pairs of monozygotic twins. Body composition measurements were performed by using the multi-frequency bioelectrical impedance technique. SCFAs were extracted from feces and quantified by gas chromatography-mass spectrometer. Gut microbiota was evaluated by 16S rRNA gene sequencing.

resultsFecal SCFAs were negatively correlated with adiposity parameters including body mass index, visceral adipose tissue and waist circumference (all

conclusionLow fecal concentrations of SCFAs were associated with visceral obesity, and the gut microbiota might be involved in the underlying mechanism.

Indexed as

gut microbiotaobesityshort-chain fatty acidstwinsvisceral fat

Identifiers

PMID35153497
PMCPMC8828081
OpenAlexW4210304104

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.