Evidence map›Paper›PMID 35153484›Full record

ReviewSubstance abuse : research and treatment2020

Aerobic Exercise Interventions for Patients in Opioid Maintenance Treatment: A Systematic Review.

Danielle E Jake-Schoffman, Meredith S Berry, Marissa L Donahue, Demetra D Christou, Jesse Dallery, Jillian M Rung

Open access · goldAbstract readReview
In one paragraph

Review in Substance abuse : research and treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Danielle E Jake-SchoffmanDepartment of Health Education and Behavior, College of Health and Human Performance, University of Florida, Gainesville, FL, USA.
Meredith S BerryDepartment of Health Education and Behavior, College of Health and Human Performance, University of Florida, Gainesville, FL, USA.
Marissa L DonahueDepartment of Health Education and Behavior, College of Health and Human Performance, University of Florida, Gainesville, FL, USA.
Demetra D ChristouDepartment of Applied Physiology and Kinesiology, College of Health and Human Performance, University of Florida, Gainesville, FL, USA.
Jesse DalleryDepartment of Psychology, College of Liberal Arts and Sciences, University of Florida, Gainesville, FL, USA.
Jillian M RungDepartment of Epidemiology, School of Public Health and Health Professions & College of Medicine, University of Florida, Gainesville, FL, USA.ORCID https://orcid.org/0000-0002-5945-6454
University of Florida · USUniversity of Florida Health · US

Funding

UF Substance Abuse Training Center in Public HealthT32DA035167 · NIDA · UNIVERSITY OF FLORIDA · PI Linda B. Cottler · 2014 to 2026
$4.8M
NIDA NIH HHS L30 DA052084NIDA NIH HHS T32 DA035167
6 · The paper itself

Abstract

backgroundOpioid maintenance treatment (OMT) is the standard for treatment of opioid use disorder, but some individuals on OMT experience disrupted sleep, heightened sensitivity to pain, and continued relapse to non-medical opioid use. An adjunctive treatment that has potential to address these shortcomings of OMT is aerobic exercise.

objectiveThe aim of the present review was to identify and evaluate components of aerobic exercise interventions targeting OMT patients.

methodsFor this PROSPERO-registered review (ID CRD42020139626), studies were identified via electronic bibliographic databases, funded research (

resultsOf 2971 unique records, three primary studies and one supplemental manuscript comprised the final sample. All studies were randomized trials involving supervised exercise interventions enrolling small samples of middle-aged OMT patients. Exercise interventions included a variety of aerobic and non-aerobic activities (e.g. flexibility exercises), and none controlled the dose of aerobic exercise. Few studies used objective measures of physical activity or cardiorespiratory fitness and there were no significant effects of adjunctive exercise on substance use outcomes, but tests of the latter were likely underpowered.

conclusionsThough early in the accumulation of evidence, interventions targeting aerobic exercise for OMT patients appear feasible, acceptable to patients, and beneficial. Longer-term studies that employ larger samples, include assessments of behavioral and biological mechanisms of change, more rigorous measurement of physical activity, and controlled doses of aerobic activity are warranted.

Indexed as

aerobic exercisemethadone maintenance treatmentopioid maintenance treatmentopioid usephysical activity

Identifiers

PMID35153484
PMCPMC8832319
OpenAlexW3035205397

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.