ArticleClinical interventions in aging2022
Intraoperative Glycemic Variability and Mean Glucose are Predictors for Postoperative Delirium After Cardiac Surgery: A Retrospective Cohort Study.
Article in Clinical interventions in aging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 20 citations in OpenAlex.
- Atherogenic Index of Plasma for the Prediction of Delirium in ICU Patients: A Retrospective Cohort Study Based on the MIMIC-IV Database.Brain and behavior · 2026Article
- Article
- Direct and indirect associations of stress hyperglycemia with delirium in older adults with community-acquired pneumonia: limited mediation by neutrophil-lymphocyte ratio and procalcitonin.BMC geriatrics · 2025Article
- The Association Between Frequency of Fingertip Blood Glucose Measurement and Delirium in Intensive Care Unit Patients: A Retrospective Study Based on the MIMIC-IV Database.Nursing in critical care · 2025Article
- Glycated Hemoglobin as a Predictor of Postoperative Delirium in Diabetic Patients Undergoing Noncardiac Surgery: A Retrospective Study.Medicina (Kaunas, Lithuania) · 2025Article
- Exploring the impact of glycemic variability on clinical outcomes in critically ill cerebral infarction patients.Diabetology & metabolic syndrome · 2025Article
- The relationship between stress hyperglycemia ratio and the risk of delirium in patients after coronary artery bypass grafting.European journal of medical research · 2025Article
- Risk factors and clinical outcome of postoperative hyperglycemia after cardiac surgery with cardiopulmonary bypass.Frontiers in cardiovascular medicine · 2025Article
- Clinical investigation into risk factors for delirium post-cardiac surgery and its implications for nursing intervention guided by behavior change theory.Journal of cardiothoracic surgery · 2024Article
- The Performance of Continuous Glucose Monitoring During the Intraoperative Period: A Scoping Review.Journal of clinical medicine · 2024Article
- Start Strong, Finish Strong: A Review of Prehabilitation in Cardiac Surgery.Life (Basel, Switzerland) · 2024Review
- Association of blood glucose change with postoperative delirium after coronary artery bypass grafting in patients with diabetes mellitus: a study of the MIMIC-IV database.Frontiers in endocrinology · 2024Article
- Taming Postoperative Delirium with Dexmedetomidine: A Review of the Therapeutic Agent's Neuroprotective Effects following Surgery.Pharmaceuticals (Basel, Switzerland) · 2023Review
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10 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposePostoperative delirium (POD) is a common but serious complication after cardiac surgery and is associated with various short- and long-term outcomes. In this study, we investigated the effects of intraoperative glycemic variability (GV) and other glycemic variables on POD after cardiac surgery. PATIENTS AND
methodsA retrospective single-center cohort analysis was conducted using data from electronic medical record from 2018 to 2020. A total of 705 patients undergoing coronary artery bypass graft surgery and/or valve surgery, and/or aortic replacement surgery were included in the analysis. Intraoperative GV was assessed with a coefficient of variation (CV), which was defined as the standard deviation of five intraoperative blood glucose measurements divided by the mean. POD assessment was performed three times a day in the ICU and twice a day in the ward until discharge by trained medical staff. POD was diagnosed if any of the Confusion Assessment Method for the Intensive Care Unit was positive in the ICU, and the Confusion Assessment Method was positive in the ward. Multivariable logistic regression was used to identify associations between intraoperative GV and POD.
resultsPOD occurred in 306 (43.4%) patients. When intraoperative glycemic CV was compared as a continuous variable, the delirium group had higher intraoperative glycemic CV than the non-delirium group (22.59 [17.09, 29.68] vs 18.19 [13.00, 23.35],
conclusionIntraoperative blood glucose fluctuation, manifested by intraoperative GV, is associated with POD after cardiac surgery. Patients with a higher intraoperative GV have an increased risk of POD.
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