ArticlePatient preference and adherence2022
Social Support and Self-Efficacy as Mediating Factors Affecting the Association Between Depression and Medication Adherence in Older Patients with Coronary Heart Disease: A Multiple Mediator Model with a Cross-Sectional Study.
Article in Patient preference and adherence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Impact of depression on medication non-adherence in coronary artery disease: a systematic review and meta-analysis.Open heart · 2025Pooled it
- From meta-analysis to Mendelian randomization: Unidirectional perspectives on the association of glaucoma with depression and anxiety.PloS one · 2024Pooled it
- The effects of PERMA model-based positive psychological intervention on fear of disease progression and subjective well-being in patients after coronary artery bypass grafting: a retrospective cohort study.Frontiers in cardiovascular medicine · 2026Article
- A qualitative study of treatment adherence from the perspective of nurses and patients following acute coronary syndrome.BMC nursing · 2025Article
- "These Drugs Are Going to Save Our Lives" A Mixed Methods Study on the Role of Medication Perceptions in Adherence to Oral Anticancer Agents Among Patients With Gastrointestinal Tract Cancer.Psycho-oncology · 2025Article
- Level of Healthcare Facility and Psychosocial Factors Influence Perceived Self-Efficacy for Appropriate Use of Hydroxyurea: Experience from Caregivers of Children with Sickle Cell Disease in Tanzania.Healthcare (Basel, Switzerland) · 2025Article
- Self-Efficacy, Social Support, and Depression: Mediators of Medication Adherence in Dialysis Patients.Healthcare (Basel, Switzerland) · 2025Article
- Relationship between social capital and medication adherence among frail and pre-frail older people: a cross-sectional study from China.BMC public health · 2025Article
- Exploring the Perceptions and Self-Perceptions of Therapeutic Adherence in Older Adults With Chronic Conditions: A Scoping Review.Patient preference and adherence · 2025Review
- Self-Care Practices and Perspectives in Managing Coronary Heart Disease Patients: A Qualitative Study.Nursing reports (Pavia, Italy) · 2024Article
- Impact of specialized nursing outpatient case management on post-coronary artery bypass grafting patients.World journal of clinical cases · 2024Article
- Article
- Social Support and Adherence to Self-Care Behavior Among Patients With Coronary Heart Disease and Heart Failure: A Systematic Review.Europe's journal of psychology · 2024Review
- Unraveling the mediation role of frailty and depression in the relationship between social support and self-management among Chinese elderly COPD patients: a cross-sectional study.BMC pulmonary medicine · 2024Article
- Perceived Determinants of Health-Related Behaviors Among Patients with Coronary Heart Disease After Percutaneous Coronary Intervention: A Longitudinal Qualitative Study.Patient preference and adherence · 2024Article
- Frailty in middle-aged and older adult postoperative patients with gynecological malignancies structural equation modeling.Frontiers in public health · 2024Article
- Mediating effects of general self-efficacy on social support and quality of life in patients after surgical aortic valve replacement.Nursing open · 2023Article
- Examining the relationship between depression and medication adherence among elderlies suffering from cardiovascular disease referring to the clinics affiliated with Kermanshah University of Medical Sciences: A cross-sectional study.Health science reports · 2023Article
- Psychopathology, Personality and Depression after Acute Coronary Syndrome: A Network Analysis in an Italian Population.Diagnostics (Basel, Switzerland) · 2023Article
- Pathways linking relative deprivation to blood pressure control: the mediating role of depression and medication adherence among Chinese middle-aged and older hypertensive patients.BMC geriatrics · 2023Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMedication non-adherence is a major public health issue. Recent evidence suggests that depression, inadequate social support, and lower levels of self-efficacy are associated with poor medication adherence. However, the mechanism underlying the association among depression, social support, self-efficacy and medication adherence is unclear. This study aims to examine the mediating role of social support and self-efficacy between depression and medication adherence in older patients with coronary heart disease. PATIENTS AND
methodsData were collected from 238 hospitalized older patients with coronary heart disease. Depression, social support, self-efficacy, and medication adherence were assessed using structured questionnaires. A serial multiple mediation model was tested using the PROCESS macro for
resultsA total of 238 older patients with CHD with a mean age of 70.5 years were involved in this cross-sectional study. Depression was negatively correlated with medication adherence in older patients with coronary heart disease. Social support and self-efficacy were positively associated with medication adherence, and fully mediated the relationship between depression and medication adherence. Three mediation paths were included in the model: (a) social support, (b) chain combination of social support and self-efficacy, and (c) self-efficacy.
conclusionSocial support and self-efficacy explain the association of depression and medication adherence in older CHD patients and may be the keys target for enhanced intervention to improve medication adherence in older CHD patients with depression.
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