Evidence map›Paper›PMID 35152887›Full record

SynthesisBMC cardiovascular disorders2022

Mortality in cardiogenic shock patients receiving mechanical circulatory support: a network meta-analysis.

Qun Zhang, Yu Han, Shukun Sun, Chuanxin Zhang, Han Liu, Bailu Wang, Shujian Wei

Open access · goldAbstract readSystematic ReviewNetwork Meta-Analysis
In one paragraph

Synthesis in BMC cardiovascular disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Qun ZhangDepartment of Emergency and Chest Pain Center, Qilu Hospital, Cheeloo College of Medicine, Shandong University, NO. 107, Jinan, 250012, Shandong, China.
Yu HanDepartment of Emergency and Chest Pain Center, Qilu Hospital, Cheeloo College of Medicine, Shandong University, NO. 107, Jinan, 250012, Shandong, China.
Shukun SunDepartment of Emergency and Chest Pain Center, Qilu Hospital, Cheeloo College of Medicine, Shandong University, NO. 107, Jinan, 250012, Shandong, China.
Chuanxin ZhangDepartment of Emergency and Chest Pain Center, Qilu Hospital, Cheeloo College of Medicine, Shandong University, NO. 107, Jinan, 250012, Shandong, China.
Han LiuDepartment of Emergency and Chest Pain Center, Qilu Hospital, Cheeloo College of Medicine, Shandong University, NO. 107, Jinan, 250012, Shandong, China.
Bailu WangClinical Trial Center, Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, 250012, Shandong, China.
Shujian WeiDepartment of Emergency and Chest Pain Center, Qilu Hospital, Cheeloo College of Medicine, Shandong University, NO. 107, Jinan, 250012, Shandong, China. weishujian@sdu.edu.cn.
Qilu Hospital of Shandong University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNMinistry of Education · THShandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveMechanical circulatory support (MCS) devices are widely used for cardiogenic shock (CS). This network meta-analysis aims to evaluate which MCS strategy offers advantages.

methodsA systemic search of PubMed, EMBASE, and the Cochrane Central Register of Controlled Trials was performed. Studies included double-blind, randomized controlled, and observational trials, with 30-day follow-ups. Paired independent researchers conducted the screening, data extraction, quality assessment, and consistency and heterogeneity assessment.

resultsWe included 39 studies (1 report). No significant difference in 30-day mortality was noted between venoarterial extracorporeal membrane oxygenation (VA-ECMO) and VA-ECMO plus Impella, Impella, and medical therapy. According to the surface under the cumulative ranking curve, the optimal ranking of the interventions was surgical venting plus VA-ECMO, medical therapy, VA-ECMO plus Impella, intra-aortic balloon pump (IABP), Impella, Tandem Heart, VA-ECMO, and Impella plus IABP. Regarding in-hospital mortality and 30-day mortality, the forest plot showed low heterogeneity. The results of the node-splitting approach showed that direct and indirect comparisons had a relatively high consistency.

conclusionsIABP more effectively reduce the incidence of 30-day mortality compared with VA-ECMO and Impella for the treatment of CS.

Indexed as

Heart, ArtificialExtracorporeal Membrane OxygenationHeart-Assist DevicesHospital MortalityHumansIntra-Aortic Balloon PumpingObservational Studies as TopicRandomized Controlled Trials as TopicRisk AssessmentRisk FactorsShock, CardiogenicTime FactorsTreatment OutcomeCardiogenic shockImpellaIntra-aortic balloon pumpMechanical circulatory supportTandem heartVenoarterial extracorporeal membrane oxygenation

Identifiers

PMID35152887
PMCPMC8842943
OpenAlexW4212854490

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.