ArticleBMC cardiovascular disorders2022
The systemic-immune-inflammation index predicts the recurrence of atrial fibrillation after cryomaze concomitant with mitral valve surgery.
Article in BMC cardiovascular disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Preprocedural systemic immune-inflammation index predicts atrial fibrillation recurrence after catheter ablation: A systematic review and meta-analysis.Biomolecules & biomedicine · 2026Pooled it
- Predictive value of neutrophil to lymphocyte ratio for clinical outcome in patients with atrial fibrillation: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Pooled it
- The Naples Prognostic Score Is Independently Associated with Paroxysmal Atrial Fibrillation: A Retrospective Case-Control Study.Journal of cardiovascular development and disease · 2026Article
- Preoperative systemic immune inflammation index predicts early complications and 30-day mortality after heart valve surgery: a retrospective cohort study.BMC anesthesiology · 2026Article
- The predictive value of the systemic immune-inflammation index in chronic thromboembolic pulmonary hypertension.Medicine · 2026Article
- Development and validation of a risk nomogram for predicting recurrence in patients with non-valvular atrial fibrillation after radiofrequency catheter ablation.BMC medical informatics and decision making · 2026Article
- Prognostic Value of Systemic Immune-Inflammation Index (SII) in Hospital Readmission Following Acute Myocardial Infarction: A Four-Year Analysis.Cardiology research and practice · 2026Article
- The association between hematological inflammatory markers and atrial fibrillation recurrence after radiofrequency ablation.Frontiers in medicine · 2026Article
- Systemic immune-inflammation Index and blood pressure control are independent and interactive predictors of atrial fibrillation recurrence after ablation.Frontiers in cardiovascular medicine · 2026Article
- The relationship between systemic immune-inflammation index and recurrence after cryoballoon ablation for paroxysmal atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025Article
- Risk Stratification in Acute Coronary Syndromes: The Systemic Immune-Inflammation Index as Prognostic Marker.Medical sciences (Basel, Switzerland) · 2025Article
- Hair Calcium Levels in Relation to Coronary Artery Disease Severity and Systemic Inflammation Markers: A Pilot Study.Journal of clinical medicine · 2025Article
- Effect of Systemic Immune-Inflammation Index on Prognosis in Non-Functional Mitral Regurgitation Patients Undergoing Isolated Mitral Valve Replacement.Brazilian journal of cardiovascular surgery · 2025Article
- Systemic immune inflammation index as a predictor for atrial fibrillation recurrence after catheter ablation.World journal of cardiology · 2025Article
- The association between blood count based inflammatory markers and the risk of atrial fibrillation heart failure and cardiovascular mortality.Scientific reports · 2025Article
- Predictive value of the systemic immune inflammation index in recurrence of atrial fibrillation after radiofrequency catheter ablation.World journal of cardiology · 2025Article
- Construction and validation of a predictive model for new-onset atrial fibrillation in patients with acute myocardial infarction following emergency percutaneous coronary intervention based on novel inflammatory markers.Frontiers in cardiovascular medicine · 2025Article
- The predictive value of pan-immune inflammatory index for early recurrence of atrial fibrillation after cryoablation.BMC cardiovascular disorders · 2024Article
- Factors predicting the recurrence of atrial fibrillation after catheter ablation: A review.Heliyon · 2024Review
- Inflammation Burden and Atrial Fibrillation Burden: A Bidirectional Relationship.Arquivos brasileiros de cardiologia · 2024Article
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Authors and funding
8 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsInflammation plays a key role in the initiation and progression of atrial fibrillation (AF). The systemic inflammation indexes are easily evaluated and predict AF development. However, it's role in prediction of recurrence of AF is unknown. We aim to explore the association between the systemic inflammation indexes and recurrence of AF in patients underwent cryoablation (CryoMaze) concomitant with mitral valve surgery.
methodsWe examined systemic inflammation indexes during perioperative period in 122 patients between 2015 and 2018. Systemic inflammation indexes were developed by systemic immune-inflammation index (SII), neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and lymphocytes to monocytes ratio. Univariate and multivariate analyses were performed to examine the association of each markers with recurrence of AF.
resultsOf the 122 patients included in this study, 22 patients (18%) experienced AF recurrence after CryoMaze concomitant with mitral valve surgery. There is no significant difference between each systemic inflammation indexes before surgery and recurrence of AF. In univariate analysis, MLR after surgery 3 days, PLR, MPLR, NLR, SII after surgery 7 days were able to predict recurrence of AF. In multivariate analyses, SII ≥ 1696 independently predicted recurrence (OR, 3.719; 95% CI, 1.417-9.760). Interestingly, baseline SII showed no significant in prediction of recurrence. It was sharply elevated after surgery and dropped slowly. In patients of recurrence, SII after 7 days of surgery increased again.
conclusionsThe raised SII again was associated with an increased risk of the postoperative recurrence of AF and independently predicted the late recurrence of AF after CryoMaze concomitant with mitral valve surgery.
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