Evidence map›Paper›PMID 35152771›Full record

ArticleThe Australian and New Zealand journal of psychiatry2022

A systematic scoping review of dissociation in borderline personality disorder and implications for research and clinical practice: Exploring the fog.

Huda F Al-Shamali, Olga Winkler, Fernanda Talarico, Andrew J Greenshaw, Christine Forner, Yanbo Zhang, Eric Vermetten, Lisa Burback

Open access · hybridAbstract readScoping Review
In one paragraph

Article in The Australian and New Zealand journal of psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 37 citations in OpenAlex.

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  13. Borderline personality disorder and sexuality: causes and consequences of dissociative symptoms.Borderline personality disorder and emotion dysregulation · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Huda F Al-ShamaliDepartment of Psychiatry, University of Alberta, Edmonton, AB, Canada.ORCID 0000-0002-3995-7075
Olga WinklerDepartment of Psychiatry, University of Alberta, Edmonton, AB, Canada.ORCID 0000-0001-7297-1250
Fernanda TalaricoDepartment of Psychiatry, University of Alberta, Edmonton, AB, Canada.ORCID 0000-0001-6114-4233
Andrew J GreenshawDepartment of Psychiatry, University of Alberta, Edmonton, AB, Canada.
Christine FornerAssociated Counselling, Calgary, AB, Canada.
Yanbo ZhangDepartment of Psychiatry, University of Alberta, Edmonton, AB, Canada.
Eric VermettenDepartment of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands.
Lisa BurbackDepartment of Psychiatry, University of Alberta, Edmonton, AB, Canada.ORCID 0000-0001-9591-4355
University of Alberta · CALeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBorderline Personality Disorder (BPD) is frequently complicated by the presence of dissociative symptoms. Pathological dissociation is linked with earlier and more severe trauma exposure, emotional dysregulation and worse treatment outcomes in Posttraumatic Stress Disorder and Dissociative Disorders, with implications for BPD.

objectiveA systematic scoping review was conducted to assess the extent of current literature regarding the impact of dissociation on BPD and to identify knowledge gaps.

methodsFour electronic databases (MEDLINE, APA PsycINFO, EMBASE, CINAHL Plus) were searched, and English peer-reviewed studies with adults with BPD were included, following Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA) extension for scoping reviews (PRISMA-ScR) 2018 guidelines.

resultsMost of the 70 included studies were observational (98%) with first authors from Germany (59%). Overall, dissociation was associated with increased BPD symptom severity, self-harm and reduced psychotherapy treatment response; findings regarding suicide risk were mixed. Dissociation was associated with working memory and cognitive deficits, decreased pain perception, altered body ownership, no substance abuse or the abuse of sedative substances, increased fantasy proneness, personality fragmentation, fearful attachment, dream anxiety, perceived stress and altered stress responses, increased cumulative body mass index, decreased water consumption, several neurological correlates and changes in gene expression.

conclusionBPD with significant dissociative symptoms may constitute a more severe and at-risk subgroup of BPD patients. However, there are significant research gaps and methodological issues in the area, including the possibility of unrecognized Dissociative Disorders in BPD study populations confounding results. Further studies are needed to better understand the impact of dissociation on BPD course and treatment, and to clarify the most appropriate assessment tools for clinical practice. In addition, interventional studies are needed to develop dissociation-specific BPD treatments to determine whether targeting dissociation in BPD can improve treatment outcomes.

Indexed as

Borderline Personality DisorderSelf-Injurious BehaviorAdultDissociative DisordersHumansHypnotics and SedativesPsychotherapyHypnotics and SedativesBorderline personality disorderdissociationdissociative disorderself-harmsuicide

Identifiers

PMID35152771
PMCPMC9511244
OpenAlexW4213188191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.