Evidence map›Paper›PMID 35152735›Full record

ArticleJournal of neurotrauma2022

Hyperbaric Oxygen Therapy after Mid-Cervical Spinal Contusion Injury.

Sara M F Turner, Michael D Sunshine, Vijayendran Chandran, Ashley J Smuder, David D Fuller

Abstract read
In one paragraph

Article in Journal of neurotrauma, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sara M F TurnerDepartment of Physical Therapy, University of Florida, Gainesville, Florida, USA.
Michael D SunshineDepartment of Physical Therapy, University of Florida, Gainesville, Florida, USA.
Vijayendran ChandranDepartment of Pediatrics, University of Florida, Gainesville, Florida, USA.
Ashley J SmuderDepartment of Breathing Research and Therapeutics Center, University of Florida, Gainesville, Florida, USA.
David D FullerDepartment of Physical Therapy, University of Florida, Gainesville, Florida, USA.

Funding

Hyperbaric oxygen therapy mitigates respiratoryneuromuscular pathology after spinal cord injuryR01HL153140 · NHLBI · UNIVERSITY OF FLORIDA · PI FULLER, DAVID D, WENDLER, CHRISTOPHER CHARLES · 2020 to 2023
$1.5M
A new method of spinal stimulation TO activate the diaphragmF31HL145831 · NHLBI · UNIVERSITY OF FLORIDA · PI SUNSHINE, MICHAEL · 2019 to 2020
$74k
NHLBI NIH HHS F31 HL145831NHLBI NIH HHS R01 HL153140
6 · The paper itself

Abstract

Hyperbaric oxygen (HBO) therapy is frequently used to treat peripheral wounds or decompression sickness. Evidence suggests that HBO therapy can provide neuroprotection and has an anti-inflammatory impact after neurological injury, including spinal cord injury (SCI). Our primary purpose was to conduct a genome-wide screening of mRNA expression changes in the injured spinal cord after HBO therapy. An mRNA gene array was used to evaluate samples taken from the contused region of the spinal cord following a lateralized mid-cervical contusion injury in adult female rats. HBO therapy consisted of daily, 1-h sessions (3.0 ATA, 100% O

Indexed as

ContusionsHyperbaric OxygenationNeck InjuriesSpinal Cord InjuriesAnimalsFemaleHumansRatsRNA, MessengerSpinal CordRNA, Messengercervicalgene arrayhyperbaric oxygenspinal cord injury

Identifiers

PMID35152735
PMCPMC9081027

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.