Evidence map›Paper›PMID 35152346›Full record

ArticleInternational urology and nephrology2022

Native kidney biopsies in older adults: disease spectrum, long-term kidney and patient survival and safety.

Hui Zhuan Tan, Benson Siow, Jason Chon Jun Choo, Alwin Hwai Liang Loh, Fiona Hui Ing Yeo, Irene Mok, Puay Hoon Tan, Choong Meng Chan, Chieh Suai Tan, Keng Thye Woo and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in International urology and nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. The Role of Desmopressin in Kidney Biopsies: A Narrative Review.Canadian journal of kidney health and disease · 2025
    Review
  5. Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Hui Zhuan TanDepartment of Renal Medicine, Singapore General Hospital, Academia Level 3, 20 College Road, Singapore, 169856, Singapore. tan.hui.zhuan@singhealth.com.sg.ORCID http://orcid.org/0000-0003-4899-6399
Benson SiowDepartment of Pharmacy, Singapore General Hospital, Singapore, Singapore.
Jason Chon Jun ChooDepartment of Renal Medicine, Singapore General Hospital, Academia Level 3, 20 College Road, Singapore, 169856, Singapore.
Alwin Hwai Liang LohDepartment of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.
Fiona Hui Ing YeoDepartment of Pharmacy, Singapore General Hospital, Singapore, Singapore.
Irene MokDepartment of Renal Medicine, Singapore General Hospital, Academia Level 3, 20 College Road, Singapore, 169856, Singapore.
Puay Hoon TanDepartment of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.
Choong Meng ChanDepartment of Renal Medicine, Singapore General Hospital, Academia Level 3, 20 College Road, Singapore, 169856, Singapore.
Chieh Suai TanDepartment of Renal Medicine, Singapore General Hospital, Academia Level 3, 20 College Road, Singapore, 169856, Singapore.
Keng Thye WooDepartment of Renal Medicine, Singapore General Hospital, Academia Level 3, 20 College Road, Singapore, 169856, Singapore.
Cynthia Ciwei LimDepartment of Renal Medicine, Singapore General Hospital, Academia Level 3, 20 College Road, Singapore, 169856, Singapore.
Singapore General Hospital · SGSingHealth · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePatients undergoing kidney biopsy are increasingly older. We aimed to evaluate the clinical utility of kidney biopsy, long-term clinical outcomes, and safety of high-risk biopsies in older adults undergoing kidney biopsy in a multi-ethnic Southeast Asian cohort.

methodsWe performed a single-center retrospective study of older patients (age ≥ 60 years) who underwent native kidney biopsies between June 2011 and March 2015. The primary long-term outcome of interest was a composite of ESKD or death. The safety outcome of interest was post-biopsy bleeding in the high-risk subgroup, defined by serum creatinine > 150 µmol/l.

resultsOlder adults accounted for 153 of 545 (28.1%) native renal biopsies performed. The median age of these older adults was 66.6 (IQR 63.0, 70.6) years. Kidney dysfunction was frequent and severe in this cohort, with 41.2% having eGFR < 30 ml/min/m

conclusionOur study confirmed the utility of kidney biopsy in older adult patients for diagnosis and management, although risk counselling and close monitoring for bleeding complications is necessary.

Indexed as

BiopsyKidneyAgedDiabetic NephropathiesHumansMiddle AgedProteinuriaRetrospective StudiesBiopsyElderlyGeriatric nephrologyGlomerulonephritis

Identifiers

PMID35152346
OpenAlexW4211040181

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.