Evidence map›Paper›PMID 35152341›Full record

ReviewMikrochimica acta2022

New trends in enzyme-free electrochemical sensing of ROS/RNS. Application to live cell analysis.

Daniel Rojas, Juan F Hernández-Rodríguez, Flavio Della Pelle, Alberto Escarpa, Dario Compagnone

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Mikrochimica acta, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Daniel RojasFaculty of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Campus "Aurelio Saliceti" via R. Balzarini 1, 64100, Teramo, Italy.
Juan F Hernández-RodríguezDepartment of Analytical Chemistry, Physical Chemistry and Chemical Engineering, Faculty of Sciences, University of Alcalá, 28871, Alcalá de Henares, Madrid, Spain.
Flavio Della PelleFaculty of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Campus "Aurelio Saliceti" via R. Balzarini 1, 64100, Teramo, Italy.
Alberto EscarpaDepartment of Analytical Chemistry, Physical Chemistry and Chemical Engineering, Faculty of Sciences, University of Alcalá, 28871, Alcalá de Henares, Madrid, Spain. alberto.escarpa@uah.es.
Dario CompagnoneFaculty of Bioscience and Technology for Food, Agriculture and Environment, University of Teramo, Campus "Aurelio Saliceti" via R. Balzarini 1, 64100, Teramo, Italy. dcompagnone@unite.it.ORCID http://orcid.org/0000-0001-7849-8943
University of Teramo · ITUniversidad de Alcalá · ES

Funding

H2020 Marie Skłodowska-Curie Actions 713714
6 · The paper itself

Abstract

The ubiquity and importance of ROS and RNS in cellular signaling, disease development, and death give rise to an outstanding interest in their detection and quantification. Among the analytical techniques available, electrochemical sensors stand out for the detection of ROS/RNS due to their high sensitivity and inherent miniaturization which allows the in situ and real-time detection together with a tunable selectivity due to the different electrochemical behavior of ROS/RNS. Nanomaterial-based enzyme-free electrochemical sensors possess improved sensitivity, selectivity, stability, and unique catalytic activities. In addition, their integration in nanoelectrodes, lab-on-chips, microfluidic systems, and stretchable electrodes allow the determination of ROS/RNS in individual cells, cell organelles, or cell populations, under different experimental conditions hardly accessible using classical detection methods.

Indexed as

Electrochemical TechniquesAnimalsCells, CulturedHumansNanostructuresReactive Nitrogen SpeciesReactive Oxygen SpeciesReactive Nitrogen SpeciesReactive Oxygen SpeciesElectrochemical sensorsLab-on-a-chipMicrofluidicsOxidative stressReactive nitrogen speciesReactive oxygen species

Identifiers

PMID35152341
OpenAlexW4212806829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.