Evidence map›Paper›PMID 35152307›Full record

ArticlePediatric surgery international2022

Impact of native nephrectomy on hypertension outcomes in pediatric kidney transplant recipients: a 10-year institutional experience.

Jin K Kim, Armando J Lorenzo, Lucshman Raveendran, Michael E Chua, Jessica M Ming, Walid A Farhat, Martin A Koyle

Abstract read
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In one paragraph

Article in Pediatric surgery international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jin K KimDivision of Urology, The Hospital for Sick Children, 555 University Ave, Toronto, ON, M5G 1X8, Canada. jjk.kim@mail.utoronto.ca.ORCID http://orcid.org/0000-0003-0964-9503
Armando J LorenzoDivision of Urology, The Hospital for Sick Children, 555 University Ave, Toronto, ON, M5G 1X8, Canada.
Lucshman RaveendranDepartment of Surgery, University of Toronto, Toronto, ON, Canada.
Michael E ChuaDivision of Urology, The Hospital for Sick Children, 555 University Ave, Toronto, ON, M5G 1X8, Canada.ORCID http://orcid.org/0000-0002-4388-4067
Jessica M MingDepartment of Surgery, University of New Mexico, Albuquerque, NM, USA.
Walid A FarhatDepartment of Urology, University of Wisconsin, Madison, WI, USA.
Martin A KoyleDivision of Urology, The Hospital for Sick Children, 555 University Ave, Toronto, ON, M5G 1X8, Canada.
University of Toronto · CAUniversity of New Mexico · USUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the role native nephrectomy (NN) in hypertension-related outcomes for pediatric patients undergoing renal transplantation (RT).

methodsRenal transplants (RT) performed at our institution between 2006 and 2015 were reviewed. RT recipients who underwent NN were compared to those who did not. Primary outcomes were hypertension-related: use/number of medications pre-/post-transplant and hypertension-related readmissions. Secondary outcomes were 1-year outcomes of: readmissions, eGFR, Clavien-Dindo classification ≥ 3 complications, and graft loss.

results135 patients were evaluated. 24 underwent NN (Group 1) and 111 did not (Group 2). Baseline characteristics were similar between Groups 1 and 2. The majority of NN indications were hypertension (10/39 kidneys) and proteinuria (12/39 kidneys). There were no differences in use/number of anti-hypertensive medications pre- or post-transplant. However, between Group 2 and subgroup of patients who underwent NN for hypertension, a significant difference was seen in medication use/numbers but not post-transplant. Number of readmissions due to hypertension was similar (7.2% vs. 12.5%). The only difference in secondary outcomes was higher readmission rates with bacterial infections for group 1 (45.8% vs. 23.4%, p = 0.041).

conclusionNN, when offered to patients at higher risk of post-RT hypertension, may allow high-risk patients to achieve similar hypertension outcomes as those at lower risk.

Indexed as

HypertensionKidney TransplantationChildHumansKidneyNephrectomyRetrospective StudiesHypertensionKidney transplantNative nephrectomyPediatric

Identifiers

PMID35152307
OpenAlexW4213055553

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.