Evidence map›Paper›PMID 35152299›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2022

Self-Assessed Severity as a Determinant of Coronavirus Disease 2019 Symptom Specificity: A Longitudinal Cohort Study.

Anna Bershteyn, Angela M Dahl, Tracy Q Dong, Meagan E Deming, Connie L Celum, Helen Y Chu, Angelica C Kottkamp, Alexander L Greninger, Risa M Hoffman, Keith R Jerome and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Anna BershteynDepartment of Population Health, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0002-6604-7093
Angela M DahlDepartment of Biostatistics, University of Washington, Seattle, Washington, USA.
Tracy Q DongVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Meagan E DemingCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Connie L CelumInternational Clinical Research Center and Department of Global Health, University of Washington, Seattle, Washington, USA.
Helen Y ChuDepartment of Medicine and Department of Epidemiology, University of Washington, Seattle, Washington, USA.
Angelica C KottkampDepartment of Medicine, New York University Grossman School of Medicine, New York, New York, USA.
Alexander L GreningerVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Risa M HoffmanDepartment of Medicine and Division of Infectious Diseases, University of California, Los Angeles, California, USA.
Keith R JeromeVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Christine M JohnstonDepartment of Medicine and Department of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.
Patricia J KissingerDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA.
Raphael J LandovitzCenter for Clinical AIDS Research & Education, University of California, Los Angeles, California, USA.
Miriam K LauferCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Alfred LukJohn W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Kathleen M NeuzilCenter for Vaccine Development and Global Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Michael K Paasche-OrlowDepartment of Medicine and Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, USA.
Robert A PittsDepartment of Medicine and Division of Infectious Diseases, NYC Health & Hospitals/Bellevue, New York, New York, USA.
Mark D SchwartzDepartment of Population Health, New York University Grossman School of Medicine, New York, New York, USA.
Helen C Stankiewicz KaritaDepartment of Medicine, University of Washington, Seattle, Washington, USA.
Lorna E ThorpeDepartment of Population Health, New York University Grossman School of Medicine, New York, New York, USA.
Anna WaldVaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Crystal Y ZhengJohn W. Deming Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Mark H WenerDepartment of Laboratory Medicine and Pathology, University of Washington, Seattle, Washington, USA.
Ruanne V BarnabasDepartment of Global Health and Department of Medicine, University of Washington, Seattle, Washington, USA.
Elizabeth R BrownDepartment of Biostatistics, University of Washington, Seattle, Washington, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 symptom definitions rarely include symptom severity. We collected daily nasal swab samples and symptom diaries from contacts of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) case patients. Requiring ≥1 moderate or severe symptom reduced sensitivity to predict SARS-CoV-2 shedding from 60.0% (95% confidence interval [CI], 52.9%-66.7%) to 31.5% (95% CI, 25.7%- 38.0%) but increased specificity from 77.5% (95% CI, 75.3%-79.5%) to 93.8% (95% CI, 92.7%-94.8%).

Indexed as

COVID-19COVID-19 TestingHumansLongitudinal StudiesSARS-CoV-2COVID-19SARS-CoV-2screeningseveritysymptoms

Identifiers

PMID35152299
PMCPMC8903379

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.