Evidence map›Paper›PMID 35151778›Full record

ArticleThe Canadian journal of cardiology2022

Care and Outcomes of ST-Segment Elevation Myocardial Infarction Across Multiple COVID-19 Waves.

Navraj Malhi, Nima Moghaddam, Farshad Hosseini, Joel Singer, Terry Lee, Ricky D Turgeon, Graham C Wong, Christopher B Fordyce

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Canadian journal of cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Navraj MalhiDivision of Cardiology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Nima MoghaddamDivision of Cardiology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Farshad HosseiniDivision of Cardiology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Joel SingerDivision of Cardiology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Centre for Health Evaluation and Outcomes Sciences, Vancouver, British Columbia, Canada.
Terry LeeDivision of Cardiology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Centre for Health Evaluation and Outcomes Sciences, Vancouver, British Columbia, Canada.
Ricky D TurgeonDivision of Cardiology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Centre for Health Evaluation and Outcomes Sciences, Vancouver, British Columbia, Canada; Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, British Columbia, Canada.
Graham C WongDivision of Cardiology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Christopher B FordyceDivision of Cardiology, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; Centre for Health Evaluation and Outcomes Sciences, Vancouver, British Columbia, Canada. Electronic address: cfordyce@mail.ubc.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are concerns of delays in ST-segment elevation myocardial infarction (STEMI) care during the COVID-19 pandemic. It is unclear whether the care and outcomes of STEMI patients differ between COVID-19 waves and compared with historical periods.

methodsConsecutive patients in the Vancouver Coastal Health Authority STEMI database were included to compare care during 3 distinct waves of the COVID-19 pandemic (9 months; March 2020 to January 2021) with an historical non-COVID-19 cohort. We compared STEMI incidence, baseline characteristics, and outcomes between groups. We also examined time from first medical contact (FMC) to reperfusion, symptom to FMC, and FMC to STEMI diagnosis, as well as predictors of delays.

resultsThe incidence of STEMI was similar during COVID-19 (n = 305; mean 0.93/day) and before COVID-19 (n = 949; 0.97/day; P = 0.80). The COVID-19 cohort showed significant delay in FMC-to-reperfusion (median 116 min vs 102 min; P < 0.001) and FMC-to-STEMI diagnosis (median 17 mins vs 11 min; P < 0.001). Delays in FMC-to-device times worsened across the 3 COVID-19 waves (FMC-to-device time ≤ 90 min in wave 1: 32.9%; in wave 2: 25.6%; in wave 3: 16.3%; P = 0.045 [47.5% before COVID-19; P < 0.001]). There were no significant predictors of delay were unique to the COVID-19 cohort.

conclusionsThis study demonstrates delays in reperfusion during the COVID-19 pandemic compared with the historical control, with delays increasing during subsequent waves within the pandemic. It is critical to further understand these care gaps to improve STEMI care for future waves of the current and future pandemics.

Indexed as

COVID-19Percutaneous Coronary InterventionST Elevation Myocardial InfarctionHumansPandemicsTime Factors

Identifiers

PMID35151778
PMCPMC8830145

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.