Evidence map›Paper›PMID 35151256›Full record

ArticleBMC medical imaging2022

Effectiveness and safety of ultrasound-guided percutaneous microwave ablation for hepatic alveolar echinococcosis.

Xu Deng, Jing-Jing Wang, Zhi-Xin Wang, Hai-Ning Fan, Hai-Jiu Wang, Han-Sheng Huang, Kai-Qaing Wang, Xiao-Zhou Yang, Jun-Wei Han, Yangdan Cairang

Open access · goldAbstract read
In one paragraph

Article in BMC medical imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xu Deng *Department of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qinghai University, Xining, China.ORCID 0000-0002-7730-2133
Jing-Jing Wang *Department of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qinghai University, Xining, China.
Zhi-Xin WangDepartment of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qinghai University, Xining, China.
Hai-Ning FanDepartment of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qinghai University, Xining, China.
Hai-Jiu WangDepartment of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qinghai University, Xining, China.
Han-Sheng HuangDepartment of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qinghai University, Xining, China.
Kai-Qaing WangDepartment of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qinghai University, Xining, China.
Xiao-Zhou YangDepartment of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qinghai University, Xining, China.
Jun-Wei HanDepartment of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qinghai University, Xining, China.
Yangdan CairangDepartment of Hepatopancreatobiliary Surgery, The Affiliated Hospital of Qinghai University, Xining, China. yangdancairang@163.com.ORCID 0000-0003-3314-3473
Qinghai University Affiliated Hospital · CNQinghai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMicrowave ablation (MWA) is a popular therapy for liver malignant tumor in recent years. Few studies have been conducted on its use in the treatment of hepatic alveolar echinococcosis (HAE). The study aims to evaluate the efficacy and safety of MWA in the treatment of HAE.

methodsThis study analyzed the data of 45 patients (mean age, 38 ± 2 years; 24 males) diagnosed with HAE and underwent MWA treatment between June 2014 to December 2019. The patients after MWA were examined by CT or MRI [follow-up: 32 months (IQR 23-48.5)] to determine whether the lesions were relapsed and to evaluate the therapeutic effect of MWA. The safety of MWA was evaluated by monitoring postoperative complications. Clinical data, such as patient demographics, imaging features of the lesions, relevant findings of laboratory tests before and after ablation, and information related to ablation, were collected and analyzed. Paired-sample t tests and paired-sample Wilcoxon signed-rank tests were used to compare relevant laboratory indicators before and after MWA.

resultsMWA was applied to 57 HAE lesions in 45 patients. The median size of lesions was 3.42 cm (IQR2.85-4.41). The rate of complete ablation was 100% (57/57). The median follow-up time was 32 months (IQR 23-48.5). The recurrence rate was 13% (6/45), and the median time of recurrence was 22 months. The rate of minor complications was 11.1% (5/45), and there were no major complications and deaths. Compared to preoperative, ALB, RBC, HBG, and PLT were decreased (p < 0.001); ALT, TB, DB, and WBC were increased (p < 0.001); and no statistically difference in PT, APTT, and INR (p > 0.05).

conclusionsMWA might be a safe and effective way to cure HAE. Meanwhile, it provides a new option and a new way of thinking about treatment for patients with HAE.

Indexed as

Ultrasonography, InterventionalAdultCatheter AblationEchinococcosis, HepaticFemaleHumansLiverMaleMicrowavesAlveolar echinococcosisHepatic alveolar echinococcosisMicrowave ablationMultilocular echinococcosis

Identifiers

PMID35151256
PMCPMC8841114
OpenAlexW4221072519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.