ArticleOsteoarthritis and cartilage2022
Excessive alcohol consumption and the risk of knee osteoarthritis: a prospective study from the Osteoarthritis Initiative.
Article in Osteoarthritis and cartilage, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Adolescence risk factors for meniscus and ligamentous knee injuries in adulthood: A longitudinal study.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- Article
- Unhealthy lifestyles accelerated aging and consequential musculoskeletal morbidity.Journal of bone and mineral metabolism · 2025Article
- Familial risks of five types of osteoarthritis in first-, second- and third-degree relatives - A nationwide Swedish family study.Osteoarthritis and cartilage open · 2025Article
- Investigating the association between calcium-phosphorus balance and osteoarthritis: Evidence from NHANES 2007-2016.Medicine · 2025Observational
- The association between the uric acid-to-high-density lipoprotein cholesterol ratio and osteoarthritis risk in U.S. adults: a cross-sectional study based on NHANES 1999-2016.Lipids in health and disease · 2025Article
- Alcohol Consumption and Autoimmune Diseases.International journal of molecular sciences · 2025Review
- Transdermal delivery of traditional Chinese medicine patch vs. NSAIDs patch for alleviating inflammation and relieving pain for early-stage knee osteoarthritis: a retrospective case control study.Frontiers in pharmacology · 2025Article
- High-intensity ethanol binge drinking accentuates bone damage in induced apical periodontitis in rats.Heliyon · 2024Article
- Factors associated with trajectories of bone marrow lesions over 4 years: data from the Osteoarthritis Initiative.Skeletal radiology · 2024Article
- Increased alcohol intake is associated with radiographic severity of knee and hand osteoarthritis in men.Scientific reports · 2024Article
- Zhuifeng Tougu capsules in the treatment of knee osteoarthritis (cold dampness obstruction syndrome): a randomized, double blind, multicenter clinical study.Chinese medicine · 2024Article
- Causal relationship between diet and knee osteoarthritis: A Mendelian randomization analysis.PloS one · 2024Article
- Plasma lipids, alcohol intake frequency and risk of Osteoarthritis: a Mendelian randomization study.BMC public health · 2023Article
- Alcoholic drink produced by pea is a risk factor for incident knee surgery in patients with knee osteoarthritis.Frontiers in nutrition · 2023Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveTo examine the association of alcohol consumption with risk of incident knee osteoarthritis (OA) in a large prospective cohort study.
designIn the Osteoarthritis Initiative, 2,846 participants aged 45-79 years and free from radiographic knee OA in at least one knee at baseline were followed up to 96 months. Information on baseline alcohol consumption was obtained from the Block Brief Food Frequency Questionnaire. Incident cases of radiographic knee OA (ROA) were defined as Kellgren-Lawrence grade changing from zero or one to ≥ two during the follow-up time. Incident symptomatic OA (SxOA) was defined as ROA with knee pain worsening. The Cox proportional hazards models were used to assess the independent association between alcohol consumption and risk of knee.
resultsDuring 96 months' follow-up, we identified 691 knees with incident ROA, and 496 knees with incident SxOA among 2,846 subjects. Compared to non-drinkers, excessive alcohol consumption was significantly associated with increased risk of ROA (HR
conclusionOur results suggest that excessive alcohol drinking was associated with an increased risk of knee OA. Further studies are needed in other populations.
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