Evidence map›Paper›PMID 35150587›Full record

ArticleAge and ageing2022

Resistance exercise as a treatment for sarcopenia: prescription and delivery.

Christopher Hurst, Sian M Robinson, Miles D Witham, Richard M Dodds, Antoneta Granic, Charlotte Buckland, Sarah De Biase, Susanne Finnegan, Lynn Rochester, Dawn A Skelton and 1 more

3 registry-linked trialsOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Age and ageing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 173 papers, 17 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
173citing papers in PubMed, 17 pooled it
30.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05982067 naunknown statusnot on this mapstarted 2023, after this paper: background citation

The Utility of MIndfulness-based Physical Exercise Program (MIPE Program) for Community-dwelling Older People With Sarcopenia: a Pilot Randomised Controlled Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2023 to 2023Enrolled60ConditionsSarcopeniaArmsmindfulness-based phsycial exercise intervention, health education
NCT06337357 narecruitingnot on this mapstarted 2024, after this paper: background citation

Evaluating Resistance Training for Sarcopenia in Older Patients With Type 2 Diabetes: Treatment Outcomes

TypeinterventionalSponsorNational Geriatric HospitalRan2024 to 2025Enrolled80ConditionsSarcopenia, DiabetesArmsProgressive Resistance Training
NCT07205133 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effectiveness of Whole Body Vibration Therapy and Usual Care Compared to Usual Care in Improving Muscle Mass, Strength and Function in Older Adults

TypeinterventionalSponsorChangi General HospitalRan2026 to 2027Enrolled40ConditionsAging, Frailty, Sarcopenia, Muscle StrengthArmsWhole Body Vibration Training, Otago Exercise
3 · Its place in the literature

Who cites it

173 citing papers in PubMed, 17 syntheses or guidelines pooled it, 281 citations in OpenAlex.

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113 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Christopher HurstAGE Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Sian M RobinsonAGE Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Miles D WithamAGE Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Richard M DoddsAGE Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Antoneta GranicAGE Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Charlotte BucklandNewcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Sarah De BiaseAGILE, Chartered Society of Physiotherapy, London, UK.
Susanne FinneganAGILE, Chartered Society of Physiotherapy, London, UK.
Lynn RochesterNewcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Dawn A SkeltonResearch Centre for Health (ReaCH), School of Health and Life Sciences, Glasgow Caledonian University, Glasgow, UK.
Avan A SayerAGE Research Group, Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Newcastle University · GBChartered Society of Physiotherapy · GBNIHR Newcastle Biomedical Research Centre · GBGlasgow Caledonian University · GB

Funding

Department of Health
6 · The paper itself

Abstract

Sarcopenia is a generalised skeletal muscle disorder characterised by reduced muscle strength and mass and associated with a range of negative health outcomes. Currently, resistance exercise (RE) is recommended as the first-line treatment for counteracting the deleterious consequences of sarcopenia in older adults. However, whilst there is considerable evidence demonstrating that RE is an effective intervention for improving muscle strength and function in healthy older adults, much less is known about its benefits in older people living with sarcopenia. Furthermore, evidence for its optimal prescription and delivery is very limited and any potential benefits of RE are unlikely to be realised in the absence of an appropriate exercise dose. We provide a summary of the underlying principles of effective RE prescription (specificity, overload and progression) and discuss the main variables (training frequency, exercise selection, exercise intensity, exercise volume and rest periods) that can be manipulated when designing RE programmes. Following this, we propose that an RE programme that consists of two exercise sessions per week and involves a combination of upper- and lower-body exercises performed with a relatively high degree of effort for 1-3 sets of 6-12 repetitions is appropriate as a treatment for sarcopenia. The principles of RE prescription outlined here and the proposed RE programme presented in this paper provide a useful resource for clinicians and exercise practitioners treating older adults with sarcopenia and will also be of value to researchers for standardising approaches to RE interventions in future sarcopenia studies.

Indexed as

Resistance TrainingSarcopeniaAgedHumansMuscle, SkeletalMuscle StrengthPrescriptionsexercise prescriptionmuscle strengtholder peoplephysical performanceresistance exercisesarcopenia

Identifiers

PMID35150587
PMCPMC8840798
OpenAlexW4205268013

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.