Evidence map›Paper›PMID 35150350›Full record

ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2022

Impact of GABA

Maryam Amjad, Atiya Tabassum, Khalid Sher, Suneel Kumar, Sitwat Zehra, Sehrish Fatima

Abstract read
PubMed Publisher
In one paragraph

Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it, 4 citations in OpenAlex.

  1. Association between theFrontiers in physiology · 2023
    Pooled it
  2. No association ofFrontiers in neurology · 2022
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Maryam AmjadThe Karachi Institute of Biotechnology and Genetic Engineering (KIBGE), University of Karachi, Karachi, 75270, Sindh, Pakistan.ORCID http://orcid.org/0000-0001-8243-1610
Atiya TabassumThe Karachi Institute of Biotechnology and Genetic Engineering (KIBGE), University of Karachi, Karachi, 75270, Sindh, Pakistan.ORCID http://orcid.org/0000-0003-1766-8317
Khalid SherDepartment of Neurology, Jinnah Postgraduate Medical Centre (JPMC), Karachi, 75510, Sindh, Pakistan.
Suneel KumarDepartment of Neurology, Jinnah Postgraduate Medical Centre (JPMC), Karachi, 75510, Sindh, Pakistan.
Sitwat ZehraThe Karachi Institute of Biotechnology and Genetic Engineering (KIBGE), University of Karachi, Karachi, 75270, Sindh, Pakistan.ORCID http://orcid.org/0000-0001-9164-6998
Sehrish FatimaThe Karachi Institute of Biotechnology and Genetic Engineering (KIBGE), University of Karachi, Karachi, 75270, Sindh, Pakistan. sehrish.fatima@kibge.edu.pk.ORCID http://orcid.org/0000-0002-6824-2677
University of Karachi · PKJinnah Postgraduate Medical Center · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epilepsy is one of the most common neurological disorders with the incidence rate higher in developing states. It is a multifactorial ailment in which genetic diversity along with other factors plays an important role. The objective of this study was to assess the involvement of different risk factors including single nucleotide polymorphisms (SNPs) present in GABRA1 (rs2279020) and GABRG2 (rs211037) genes with the susceptibility to epilepsy in the targeted population. Blood samples of 180 subjects were taken and genotyped through tetra-primer amplification refractory mutation system-polymerase chain reaction technique. The obtained demographic and genotypic data were analyzed through different statistical tools including χ

Indexed as

EpilepsyReceptors, GABA-ACase-Control StudiesFemaleGenetic Predisposition to DiseaseGenotypeHumansMalePolymorphism, Single NucleotideGABRA1 protein, humanGABRG2 protein, humanReceptors, GABA-AEpilepsyGABRA1GABRG2Pakistanrs211037rs2279020

Identifiers

PMID35150350
OpenAlexW4211163760

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.