Evidence map›Paper›PMID 35150287›Full record

ReviewDiabetologia2022

Lifestyle interventions in pregnancy targeting GDM prevention: looking ahead to precision medicine.

Joshua R Sparks, Nidhi Ghildayal, Marie-France Hivert, Leanne M Redman

Open access · bronzeAbstract readReview
In one paragraph

Review in Diabetologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. [A randomized controlled trial of weight management based on mobile health techno-logy among overweight or obese pregnant women].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025
    Trial
  5. Trial
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Joshua R SparksReproductive Endocrinology and Women's Health Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, USA.
Nidhi GhildayalDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Harvard University, Boston, MA, USA.
Marie-France HivertDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Harvard University, Boston, MA, USA. mhivert@partners.org.
Leanne M RedmanReproductive Endocrinology and Women's Health Laboratory, Pennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, USA. Leanne.Redman@PBRC.edu.
Harvard University · USLouisiana State University · USPennington Biomedical Research Center · US

Funding

Research BaseP30DK072476 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI ROBERT A KESTERSON · 2005 to 2026
$26.5M
Preventing excessive gestational weight gain in obese womenU01HL114377 · NHLBI · CALIFORNIA POLY STATE U SAN LUIS OBISPO · PI PHELAN, SUZANNE · 2011 to 2016
$4.5M
Impact of insulin-like growth factors and binding proteins on gestational diabetes and fetal growthR01HD094150 · NICHD · HARVARD PILGRIM HEALTH CARE, INC. · PI Marie-France Hivert, Camille Elise Powe · 2018 to 2026
$4.2M
A pragmatic, scalable e-health intervention for management of gestational weight gain in low-income mothersR01NR017644 · NINR · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI REDMAN, LEANNE MAREE · 2019 to 2024
$3.6M
Promoting fat loss during pregnancy in women with grade 2 and 3 obesityR01DK124806 · NIDDK · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI PHELAN, SUZANNE, REDMAN, LEANNE MAREE · 2020 to 2024
$3.2M
Prevention of postparutm weight retention in low income WIC womenR01DK087889 · NIDDK · CALIFORNIA POLY STATE U SAN LUIS OBISPO · PI PHELAN, SUZANNE · 2011 to 2015
$3.0M
Prevention of gestational diabetes through lifestyle modification before pregnancyR01HD084282 · NICHD · CALIFORNIA POLY STATE U SAN LUIS OBISPO · PI PHELAN, SUZANNE · 2016 to 2020
$2.8M
Meal time interactions and risk of obesity in toddlersR01DK108661 · NIDDK · TEMPLE UNIV OF THE COMMONWEALTH · PI HART, CHANTELLE NOBILE, PHELAN, SUZANNE · 2016 to 2019
$2.3M
Prevention of Postpartum Weight RetentionR01DK071667 · NIDDK · MIRIAM HOSPITAL · PI WING, RENA R · 2006 to 2009
$1.5M
Healthy Hearts/ Corazones Saludables: Partnership to promote cardiovascular health in Hispanic and non-Hispanic mothers and children in US home visiting programsUG3HL163508 · NHLBI · CALIFORNIA POLY STATE U SAN LUIS OBISPO · PI PARADE, STEPHANIE HART, PHELAN, SUZANNE · 2022 to 2023
$1.3M
Meal time interactions and risk of obesity in toddlersR56DK108661 · NIDDK · TEMPLE UNIV OF THE COMMONWEALTH · PI HART, CHANTELLE NOBILE, PHELAN, SUZANNE · 2015 to 2015
$125k
NHLBI NIH HHS U01 HL114377NHLBI NIH HHS UG3 HL163508NICHD NIH HHS R01 HD084282NICHD NIH HHS R01 HD094150NIDDK NIH HHS P30 DK072476NIDDK NIH HHS R01 DK071667NIDDK NIH HHS R01 DK087889NIDDK NIH HHS R01 DK108661NIDDK NIH HHS R01 DK124806NIDDK NIH HHS R56 DK108661NINR NIH HHS R01 NR017644
6 · The paper itself

Abstract

Gestational diabetes mellitus (GDM) is the most prevalent pregnancy-related endocrinopathy, affecting up to 25% of pregnancies worldwide. Pregnant individuals who develop GDM have an increased risk of complications during pregnancy and birth, as well as future development of type 2 diabetes mellitus and CVD. This increased risk is subsequently passed along to the offspring, perpetuating a cycle of metabolic dysfunction across generations. GDM prevention strategies have had mixed results for many years, but more recent systematic reviews and meta-analyses have suggested potential new avenues of prevention. The objective of this review is to summarise the literature examining the efficacy of lifestyle interventions for the prevention of GDM and to uncover if specific individual-level characteristics influence this outcome. Based on the present literature, we determined that future trials should be designed to understand if initiation of lifestyle intervention in the preconception period is more effective to reduce GDM. Furthermore, trials initiated during pregnancy should be developed through the lens of precision prevention. That is, trials should tailor intervention approaches based on individual-level risk defined by the presence of modifiable and non-modifiable risk factors. Finally, future interventions might also benefit from just-in-time adaptive intervention designs, which allow for interventions to be modified in real-time based on objective assessments of an individual's response.

Indexed as

Diabetes, GestationalDiabetes Mellitus, Type 2ExerciseFemaleHumansLife StylePrecision MedicinePregnancyBehaviourDietExerciseGestational diabetes mellitus (GDM)IndividualLifestylePersonalised medicinePrecision medicinePredictionPrescriptionResponseReview

Identifiers

PMID35150287
PMCPMC10994387
OpenAlexW4211191703

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.