Evidence map›Paper›PMID 35149989›Full record

ArticleEvolution; international journal of organic evolution2022

Digest: Stable phenotypes, fluid genotypes: how stochasticity impacts network evolution and speciation.

Maddie E James, Nicholas L V O'Brien, Anuraag Bukkuri

Open access · hybridAbstract readNewsComment
In one paragraph

Article in Evolution; international journal of organic evolution, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Risk Factors and Mechanisms Leading to Preschool Recurrent Wheeze and Asthma.The journal of allergy and clinical immunology. In practice · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Maddie E JamesAustralian Research Council Centre of Excellence for Plant Success in Nature and Agriculture, The University of Queensland, St Lucia, QLD, 4072, Australia.ORCID 0000-0001-6296-0187
Nicholas L V O'BrienAustralian Research Council Centre of Excellence for Plant Success in Nature and Agriculture, The University of Queensland, St Lucia, QLD, 4072, Australia.ORCID 0000-0003-1363-5841
Anuraag BukkuriCancer Biology and Evolution Program and Department of Integrated Mathematical Oncology, Moffitt Cancer Center, Tampa, Florida, 33612.ORCID 0000-0002-3616-626X
Australian Research Council · AUMoffitt Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A longstanding goal of evolutionary biology is to understand the relationship between genotype and phenotype. Schiffman and Ralph use mathematical modeling to theoretically examine how the genetic network underlying a conserved phenotype can change over time. They found that when phenotypically identical populations with different gene network configurations interbreed, hybrid incompatibilities can arise. These results suggest that neutral processes could play a major role in driving speciation.

Indexed as

Biological EvolutionHybridization, GeneticGene Regulatory NetworksGenetic SpeciationGenotypeModels, GeneticPhenotype

Identifiers

PMID35149989
PMCPMC9303642
OpenAlexW4211032461

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.