Evidence map›Paper›PMID 35149967›Full record

ReviewPulmonary therapy2022

Cystic Fibrosis and Sleep Circadian Rhythms.

Mariam Louis, Peter Staiano, Lavender Micalo, Nauman Chaudary

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Pulmonary therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Mariam LouisDepartment of Pulmonary, Critical Care and Sleep Medicine, University of Florida, Jacksonville, FL, USA.
Peter StaianoDepartment of Pulmonary, Critical Care and Sleep Medicine, University of Florida, Jacksonville, FL, USA.
Lavender MicaloDivision of Pulmonary Disease and Critical Care Medicine, Department of Medicine, Adult Cystic Fibrosis Center, Virginia Commonwealth University, 1200 East Broad Street, Box 980050, Richmond, VA, 23298, USA.
Nauman ChaudaryDivision of Pulmonary Disease and Critical Care Medicine, Department of Medicine, Adult Cystic Fibrosis Center, Virginia Commonwealth University, 1200 East Broad Street, Box 980050, Richmond, VA, 23298, USA. nauman.chaudary@vcuhealth.org.
University of Florida · USVirginia Commonwealth University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cystic fibrosis (CF) is due to a mutation in the cystic fibrosis transmembrane conductance regulator gene (CFTR), which leads to unusual water and chloride secretion across epithelial surfaces. The lungs are responsible for most morbidity, though other organs are frequently affected. Sleep abnormalities have long been recognized in CF. Abnormal ventilation and oxygenation, sinus disease, deconditioning due to muscle weakness and recurrent infections, and inflammation have been thought to play a role in sleep disorders in CF. However, there is evidence that CFTR gene dysregulation can affect circadian rhythms in CF. Early recognition and treatment of circadian rhythms may improve outcomes in CF.

Indexed as

CFTR dysregulationCircadian rhythmCystic fibrosisSleep disordersSleep quality

Identifiers

PMID35149967
PMCPMC9098776
OpenAlexW4210991814

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.