Evidence map›Paper›PMID 35149923›Full record

ArticleInternational ophthalmology2022

A Delphi study on the clinical management of age-related macular degeneration.

Nuno Gomes, Angelina Meireles, Ângela Carneiro, Rufino Silva, António Campos, Lilianne Duarte, Rita Flores, Carlos Marques-Neves, Portuguese RAMD consensus group

Abstract read
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In one paragraph

Article in International ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nuno GomesDepartamento de Retina Do Hospital de Braga, Rua das Comunidades Lusíadas 133, Braga, Portugal. nunolgomes@gmail.com.
Angelina MeirelesDepartment of Ophthalmology, Hospital de Santo António, Centro Hospitalar Universitário Do Porto, Porto, Portugal.ORCID http://orcid.org/0000-0001-9148-2786
Ângela CarneiroDepartment of Ophthalmology, Centro Hospitalar Universitário de São João, Porto, Portugal.ORCID http://orcid.org/0000-0002-3370-7243
Rufino SilvaDepartment of Ophthalmology, Centro Hospitalar Universitário de Coimbra, Coimbra, Portugal.ORCID http://orcid.org/0000-0001-8676-0833
António CamposDepartment of Ophthalmology, Centro Hospitalar de Leiria, Leiria, Portugal.ORCID http://orcid.org/0000-0003-0490-5889
Lilianne DuarteDepartment of Ophthalmology, Centro Hospitalar de Entre O Douro E Vouga, Santa Maria da Feira, Portugal.ORCID http://orcid.org/0000-0003-3953-0730
Rita FloresDepartment of Ophthalmology, Centro Hospitalar Lisboa Central, Lisboa, Portugal.ORCID http://orcid.org/0000-0002-7523-2418
Carlos Marques-NevesFaculdade de Medicina da Universidade de Lisboa, University Ophthalmology Clinic, Lisboa, Portugal.ORCID http://orcid.org/0000-0002-3842-2466
Portuguese RAMD consensus group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAge-related macular degeneration (AMD) is one of the main causes of blindness and visual impairment worldwide. As achieving a dry macula is one of the main objectives in AMD management, the purpose of this work was to reach a consensus on the relevance of retinal fluid in function, disease activity control and treatment patterns.

methodsForty-seven Portuguese ophthalmologists specialized in AMD participated in a DELPHI panel. Two rounds of presential meetings were conducted and a cut-off of 80% or more of votes was defined to consider answers consensual.

resultsConsensus was reached for 11 out of 18 questions. These questions focused on the impact of anatomical results on visual acuity, standards exams and parameters to assess disease activity, frequency and factors which influence disease activity assessment, criteria to use non-fixed treatment regimens, usefulness of individualized regimens and conditions for treatment interruption. No consensus was obtained for relevance of the different fluid types in AMD prognosis, frequency of fluid presence assessment, factors commonly associated with progression to geographic atrophy, ideal conditions for a fixed treatment regimen, date of first disease activity assessment and parameters to monitor disease activity.

conclusionsConsensus was achieved for over half of the questions assessed through this Delphi study. The questions for which no consensus was reached concerned either subjects that need further investigation or monitoring times which are influenced by resource availability. Raising awareness for these issues will allow the improvement of AMD management and treatment.

Indexed as

Geographic AtrophyMacula LuteaMacular DegenerationWet Macular DegenerationDelphi TechniqueHumansVisual AcuityAge-related macular degenerationConsensusDisease activityDisease managementRetinal fluidTreatment regimen

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.