Evidence map›Paper›PMID 35149907›Full record

Trial reportPlant foods for human nutrition (Dordrecht, Netherlands)2022

Daily Intake of Lemna minor or Spinach as Vegetable Does Not Show Significant Difference on Health Parameters and Taste Preference.

Jurriaan J Mes, Diederik Esser, Dianne Somhorst, Els Oosterink, Sandra van der Haar, Meeke Ummels, Els Siebelink, Ingrid M van der Meer

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Plant foods for human nutrition (Dordrecht, Netherlands), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Duckweed (Frontiers in nutrition · 2026
    Review
  3. Modeling Growth Dynamics ofPlants (Basel, Switzerland) · 2025
    Article
  4. Foods (Basel, Switzerland) · 2024
    Review
  5. Article
  6. Article
  7. Safety ofEFSA journal. European Food Safety Authority · 2022
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jurriaan J MesWageningen Food & Biobased Research, Wageningen University & Research, Bornse Weilanden 9, 6708, WG, Wageningen, The Netherlands. jurriaan.mes@wur.nl.ORCID http://orcid.org/0000-0002-3589-8434
Diederik EsserWageningen Food & Biobased Research, Wageningen University & Research, Bornse Weilanden 9, 6708, WG, Wageningen, The Netherlands.
Dianne SomhorstWageningen Food & Biobased Research, Wageningen University & Research, Bornse Weilanden 9, 6708, WG, Wageningen, The Netherlands.
Els OosterinkWageningen Food & Biobased Research, Wageningen University & Research, Bornse Weilanden 9, 6708, WG, Wageningen, The Netherlands.
Sandra van der HaarWageningen Food & Biobased Research, Wageningen University & Research, Bornse Weilanden 9, 6708, WG, Wageningen, The Netherlands.
Meeke UmmelsWageningen Food & Biobased Research, Wageningen University & Research, Bornse Weilanden 9, 6708, WG, Wageningen, The Netherlands.
Els SiebelinkDivision of Human Nutrition & Health, Wageningen University & Research, Stippeneng 4, 6708, WE, Wageningen, The Netherlands.
Ingrid M van der MeerWageningen Plant Research, Bioscience, Wageningen University & Research, Droevendaalsesteeg 1, 6708, PB, Wageningen, The Netherlands.
Wageningen University & Research · NL

Funding

Wellcome TrustWellcome Trust 106876/Z15/Z
6 · The paper itself

Abstract

The growing world population will increase the demand for new sustainable foods and ingredients. Here we studied the safety and tolerance of Lemna minor, a new sustainable vegetable crop from the duckweed family. Twenty-four healthy adults consumed either L. minor plant material or spinach as vegetable (170 g fresh weight) as part of a warm meal on 11 consecutively days in a randomized controlled parallel trial design. The intervention meals had a different recipe for each day of the week. All participants had to report daily if they experienced gastric complaints, feelings of hunger, fullness, desire to eat, thirst, general health, nausea, and stool consistency. Only hunger, flatulence and constipation were significantly different between both intervention groups. At the start and end of the intervention, blood and urine were sampled in order to analyze biomarkers for general health, e.g., kidney function, liver function, cardiovascular health, inflammation and iron status. Both intervention groups did not show significant differences for these biomarkers. In taste attributes the L. minor-based products showed in only a few specific cases a significant difference compared to the spinach-based products. Based on the results we conclude that 11 consecutive days intake of 170 g fresh weight L. minor plants as a cooked vegetable does not result in any adverse effect in healthy adult subjects.

Indexed as

AraceaeSpinacia oleraceaTasteVegetablesEnergy IntakeFood PreferencesHumansAdverse eventsDuckweedSafetySustainable vegetableTasteTolerance

Identifiers

PMID35149907
PMCPMC8993727
OpenAlexW4211148679

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.