Trial reportClinical oral investigations2022
Bonding performance and ultramorphology of the resin-dentine interface of contemporary universal adhesives.
Trial report in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Comparison of universal adhesives used in different etching modes on dentin bond strength: a systematic review and network meta-analysis.BMC oral health · 2026Pooled it
- Influence of Etching Protocols on the Bonding Stability of Universal Adhesives to Dentin.Polymers · 2026Article
- The Effects of Immediate Dentin Sealing on the Enzymatic Activity and Bond Strength of Hybrid Ceramic CAD/CAM Onlays: A Comparative Study of Two Universal Adhesives.Dentistry journal · 2026Article
- Microtensile bond strength and dentin-adhesive interface of universal adhesives before and after artificial aging: an in vitro study.Scientific reports · 2026Article
- Development of multifunctional dental adhesive with 4-formylphenyl acrylate and nano-silver.Clinical oral investigations · 2026Article
- Effect of different dentin etching protocols on the immediate microtensile bond strength of two bulk-fill restorative systems in class I cavities.BMC oral health · 2026Article
- Bioactive and Ion-releasing materials in minimum intervention dentistry: a clinical pathway from prevention to restorative treatment.Frontiers in dental medicine · 2026Article
- Internal adaptation and micromorphological analysis of a new self-cure resin composite.Journal of clinical and experimental dentistry · 2025Article
- Synergistic strategy of riboflavin and lipoids to bioengineer resin dentin hybrid layer.Scientific reports · 2025Article
- Influence of Academic Training and Professional Experience on the Management of Deep Caries Lesions.Healthcare (Basel, Switzerland) · 2024Article
- Bonding performance and interfacial adaptation of modern bulk-fill restorative composites after aging in artificial saliva: an in vitro study.Clinical oral investigations · 2024Article
- Dentine Remineralisation Induced by "Bioactive" Materials through Mineral Deposition: An In Vitro Study.Nanomaterials (Basel, Switzerland) · 2024Article
- Comparison of Adhesion Performance of a Self-curing and a Light-curing Universal Adhesive to Various Dental Substrates and CAD/CAM Materials.The journal of adhesive dentistry · 2024Article
- Marginal Integrity of Simplified Adhesive Strategies in Primary Teeth.International dental journal · 2023Article
- Effect of Modified Triple-Layer Application on the Bond Strength of Different Dental Adhesive Systems to Dentin.Journal of functional biomaterials · 2023Article
- The potential use of glycosyl-transferase inhibitors for targeted reduction of S. mutans biofilms in dental materials.Scientific reports · 2023Article
- Long-Term In Vitro Adhesive Properties of Two Universal Adhesives to Dentin.Materials (Basel, Switzerland) · 2023Article
- Surface Treatments on Repair Bond Strength of Aged Resin Composites.Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 4 countries.
Funding
Abstract
objectivesThis study aimed at evaluating the microtensile bond strength (μTBS) and the resin-dentine ultramorphology (24 h and 10 months ageing) of contemporary universal adhesives applied in self-etch (SE) or etch-and-rinse (ER) mode. MATERIALS AND
methodsSixty-four sound human molars were collected and randomly allocated in 4 main experimental groups (n = 16) according to the adhesive system employed and subsequently divided into two subgroups depending on their application mode SE or ER (n = 8): ZipBond X (ZBX-SE; ZBX-ER), Prime and Bond Active (PBA-SE; PBA-ER), Clearfil Universal Bond Quick (CBQ-SE; CBQ-ER) or Scotchbond Universal (SCH-SE; SCH-ER). The specimens were cut into sticks with a cross-sectional area of approximately 0.9 mm
resultsZBX, PBA and SCH exhibited greater μTBS values than CQB at 24 h in both SE and ER modes (p < 0.05). CQB showed a significant decrease in μTBS values after ageing both when used in SE and ER mode (p < 0.05). ZBX-ER exhibited no significant differences in the μTBS test after ageing (p > 0.05), while a significant drop in μTBS was seen in SCH-ER and APB-ER after 10-month ageing (p < 0.05). Clear signs of degradation were evident in the resin-dentine interface created with CQB regardless of the application mode or the ageing time. In APB-ER and SCH-ER groups, such signs of degradation were evident after ageing in AS. ZBX showed slight dye infiltration both when used in ER and SE mode.
conclusionsThe long-term bonding performance of modern universal adhesives is usually influenced by the adhesive strategy employed; self-etching application should be prioritised during dentine bonding. Moreover, the use of shortened bonding protocols may compromise the quality of the resin-dentine interface and the bonding performance of most modern universal adhesives. CLINICAL RELEVANCE: The use of etch-and-rinse bonding procedures, as well as "shortened" application protocols should be eluded when using modern universal adhesives in dentine. However, new generation universal adhesives based on innovative chemical formulations may probably allow clinicians to achieve long-term bonding performance with such simplified system also when employed in ER mode.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.