Evidence map›Paper›PMID 35149899›Full record

SynthesisJournal of cancer survivorship : research and practice2023

Effects of exercise on chemotherapy-induced peripheral neuropathy in cancer patients: a systematic review and meta-analysis.

Shaoning Guo, Wenwen Han, Pengju Wang, Xue Wang, Xuedong Fang

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of cancer survivorship : research and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 5 pooled it
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 5 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
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  3. BeyondFrontiers in pain research (Lausanne, Switzerland) · 2025
    Pooled it
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  8. Lending a hand: supportive exercise therapy for cancer treatment-induced polyneuropathy of the upper extremity-VISCIPH A.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Trial
  9. The effect of hand and foot exercises on peripheral neuropathy and quality of life in women with breast cancer: a randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  17. The relationship between sexual activity during chemotherapy and sexual functioning after treatment among females with breast and gynecologic cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Shaoning GuoSchool of Nursing, Jilin University, 965 Xinjiang Street, Changchun, 130021, Jilin, China.ORCID 0000-0002-7003-4455
Wenwen HanDepartment of Nursing, The First Bethune Hospital of Jilin University, Changchun, 130021, Jilin, China.ORCID 0000-0001-7641-1824
Pengju WangDepartment of Nursing, The First Bethune Hospital of Jilin University, Changchun, 130021, Jilin, China.ORCID 0000-0001-7450-025X
Xue WangSchool of Nursing, Changchun University of Chinese Medicine, Changchun, 130117, Jilin, China.ORCID 0000-0002-9886-4581
Xuedong FangDepartment of Gastrointestinal Colorectal and Anal Surgery, China-Japan Union Hospital of Jilin University, Changchun, 130033, Jilin, China. guoshaoning@jlu.edu.cn.ORCID 0000-0002-1382-5373
First Bethune Hospital of Jilin University · CNJilin University · CNChangchun University of Chinese Medicine · CN

Funding

Jilin Province Department of Finance JLSCZN2019-004
6 · The paper itself

Abstract

purposeSummarize and critically evaluate the existing studies to determine the effects of exercise on chemotherapy-induced peripheral neuropathy in cancer patients.

methodsWe searched PubMed, Scopus, Web of Science, and Cochrane Library databases for randomized controlled trials reporting exercise intervention in cancer patients with chemotherapy-induced peripheral neuropathy. The outcomes of interest included chemotherapy-induced peripheral neuropathy symptoms, physical function (balance control, muscle strength, and functional status), and quality of life. The Cochrane Collaboration's tool was employed to assess the risk of bias.

resultsThe search identified 1309 studies, 16 of which eligible. Our meta-analysis revealed that exercise intervention significantly improved the quality of life (SMD = 0.83, 95% CI = 0.58 to 1.08, I

conclusionsThe results of this study showed that combined exercise could be an effective option for improving quality of life, physical function (balance control and muscle strength), and neuropathic pain in cancer patients with chemotherapy-induced peripheral neuropathy. Further exploration of appropriate exercise prescriptions is needed to improve other outcomes. IMPLICATIONS FOR CANCER SURVIVORS: Specific and appropriate exercise intervention for cancer patients with chemotherapy-induced peripheral neuropathy should be recommended because these interventions can improve their quality of life and physical function.

Indexed as

Antineoplastic AgentsCancer SurvivorsNeoplasmsNeuralgiaHumansQuality of LifeAntineoplastic AgentsCancerChemotherapy-induced peripheral neuropathyExerciseSystematic review

Identifiers

PMID35149899
OpenAlexW4211078013

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.