Evidence map›Paper›PMID 35149883›Full record

ArticleNeuroradiology2022

Comparison between 3D SPACE FLAIR and 3D TSE FLAIR in Menière's disease.

Anja Bernaerts, Nick Janssen, Floris L Wuyts, Cathérine Blaivie, Robby Vanspauwen, Joost van Dinther, Andrzej Zarowski, Erwin Offeciers, Filip Deckers, Jan W Casselman and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Neuroradiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
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  7. [Artificial intelligence applications in Ménière's disease].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Anja BernaertsDepartment of Radiology, GZA Hospitals Antwerp, Oosterveldlaan 24, 2610, Antwerp, Belgium. Anja.Bernaerts@gza.be.ORCID http://orcid.org/0000-0002-8652-7967
Nick JanssenDepartment of Radiology, GZA Hospitals Antwerp, Oosterveldlaan 24, 2610, Antwerp, Belgium.
Floris L WuytsLab for Equilibrium Investigations and Aerospace, University of Antwerp, Universiteitsplein 1, 2610, Antwerp, Belgium.
Cathérine BlaivieEuropean Institute for ORL-HNS, GZA Hospitals Antwerp, Oosterveldlaan 24, 2610, Antwerp, Belgium.
Robby VanspauwenEuropean Institute for ORL-HNS, GZA Hospitals Antwerp, Oosterveldlaan 24, 2610, Antwerp, Belgium.
Joost van DintherEuropean Institute for ORL-HNS, GZA Hospitals Antwerp, Oosterveldlaan 24, 2610, Antwerp, Belgium.
Andrzej ZarowskiEuropean Institute for ORL-HNS, GZA Hospitals Antwerp, Oosterveldlaan 24, 2610, Antwerp, Belgium.
Erwin OffeciersEuropean Institute for ORL-HNS, GZA Hospitals Antwerp, Oosterveldlaan 24, 2610, Antwerp, Belgium.
Filip DeckersDepartment of Radiology, GZA Hospitals Antwerp, Oosterveldlaan 24, 2610, Antwerp, Belgium.
Jan W CasselmanDepartment of Radiology, GZA Hospitals Antwerp, Oosterveldlaan 24, 2610, Antwerp, Belgium.
Bert De FoerDepartment of Radiology, GZA Hospitals Antwerp, Oosterveldlaan 24, 2610, Antwerp, Belgium.
GZA Ziekenhuizen Campus Sint-Augustinus · BEUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeHeavily T2-weighted 3D FLAIR (hT

methodsThis retrospective study included 29 definite MD patients who underwent a 4-h delayed intravenous (IV) Gd-enhanced 3D-TSE FLAIR and 3D-SPACE FLAIR MRI between February 2019 and February 2020. MR images were qualitatively and quantitatively analyzed twice by 2 experienced head and neck radiologists. Qualitative assessment included grading of cochlear and vestibular EH and visual comparison of PE. Quantitative assessment of PE was performed by placing a region of interest (ROI) and ratio calculation in the basal turn of the cochlea and the brainstem.

resultsThe intra- and inter-reader reliability for grading of EH and PE was excellent (0.7 < kappa < 0.9) for 3D-SPACE FLAIR and exceeded the values for 3D-TSE FLAIR (0.5 < kappa < 0.9) The combination of EH and visual assessment of PE has the highest diagnostic accuracy in diagnosing definite MD on 3D-SPACE FLAIR with a sensitivity of 0.91 and a specificity of 0.98 resulting in a sensitivity raise of 6% compared to 3D-TSE FLAIR.

conclusionFour-hour delayed IV Gd-enhanced 3D-SPACE FLAIR sequence has a higher sensitivity and reproducibility than 3D-TSE FLAIR for the visualization of EH and increased PE in definite MD patients.

Indexed as

Endolymphatic HydropsMeniere DiseaseContrast MediaGadoliniumHumansImaging, Three-DimensionalMagnetic Resonance ImagingReproducibility of ResultsRetrospective StudiesContrast MediaGadoliniumDiagnosisEndolymphatic hydropsMagnetic resonance imagingMenière diseasePerilymph

Identifiers

PMID35149883
PMCPMC9005391
OpenAlexW4211038907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.